In the yeast Saccharomyces cerevisiae, peptide mating pheromones activate a signal transduction pathway that leads to cellular differentiation and cell division cycle arrest. It is now possible to trace the major events of this pathway. binding of pheromone to G-protein-coupled receptors activates a ...
In the yeast Saccharomyces cerevisiae, peptide mating pheromones activate a signal transduction pathway that leads to cellular differentiation and cell division cycle arrest. It is now possible to trace the major events of this pathway. binding of pheromone to G-protein-coupled receptors activates a ...
TITLE: Inhibition of the yeast mating pathway by Kluyveromyces lactis and Pichia acaciae toxins ABSTRACT The mating pathway of Saccharomyces cerevisiae is inhibited by the toxins produced by Kluyveromyces lactis and Pichia acaciae. This effect is independent of the cell cycle arrest characteristic of t...
The mating pathway in Saccharomyces cerevisiae is one of the best understood signal transduction pathways in eukaryotes. It transmits the mating signal from plasma membrane into the nucleus through the G-protein coupled receptor and the mitogen-activated protein kinase (MAPK) cascade. According to cur...
The intracellular signal transduction pathway by which the yeast Saccharomyces cerevisiae responds to the presence of peptide mating pheromone in its surroundings is one of the best understood signaling pathways in eukaryotes, yet continues to generate new surprises and insights. In this review, we take...
Signal transduction in the mating pathway of the yeast Saccharomyces cerevisiae is initiated by binding of a peptide pheromone to a G protein-coupled receptor (Ste2). We systematically have mutated the third intracellular loop of the Ste2 receptor to investigate its functional significance. We substi...
Pheromone response and signal transduction during the mating process of Saccharomyces cerevisiae I. INTRODUCTION As an alternative to vegetative (mitotic) proliferation, the two different haploid cell types ( a cells and 伪 cells) of Saccharomyces cerevisiae are able to conjugate ("mate") to form di...
which regulates the mating pathway and complemented the signaling defect of theste4mutant75;STE7,the MAPKK that regulates the mating and fMAPK pathways76;BMH1andBMH2, which are members of the 14-3-3 family of proteins and are established regulators of the fMAPK pathway7, andMIG2a transcripti...
Brewster JL, de Valoir T, Dwyer ND, Winter E, Gustin MC . (1993). An osmosensing signal transduction pathway in yeast.Science259: 1760–1763. ArticleCASGoogle Scholar Chan RK, Otte CA . (1982a). Isolation and genetic analysis ofSaccharomyces cerevisiaemutants supersensitive to G1 arrest by...
Yeast harbor a single canonical G protein signaling system, the pheromone response pathway, responsible for the signal transduction of peptide mating pheromones that are secreted and exchanged between haploid yeast cells of opposite mating types. As with mammalian G protein signaling systems, the binding...