The formation and maintenance of subcellular structures and organelles with a well-defined size is a key requirement for cell function, yet our understanding of the underlying size control mechanisms is limited. While budding yeast cell polarization and
Sizing up to Divide: Mitotic Cell-Size Control in Fission Yeast Schizosaccharomyces pombe is a good model to study cell-size control. These cells integrate size information into cell cycle controls at both the G1/S and ... E Wood,P Nurse - 《Annual Review of Cell & Developmental Biology》...
ReviewImportantYeastGeneGeneticsStudyYeasts are unicellular fungi taxonomical classifications under the phylum Ascomycetes, classHemiascomycetes. S. cerevisiae has been the model system for much of molecular genetic research because thebasic cellular mechanics of replication, recombination, cell division and ...
This review gives an overview of different yeast strains and enzyme classes involved in yeast whole-cell biotransformations. A focus was put on the synthesis of compounds for fine chemical and API (= active pharmaceutical ingredient) production employing single or only few-step enzymatic reactions. A...
ThomasStrahl,JeremyThorner, inBiochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2007 In this article, we provide an overview of the various PIPs that have been identified as physiologically relevant to the biology ofS. cerevisiae. We also review what is currently known...
Full size image Cooperativity and antagonism may be mechanisms by which tissue- and cell type-specific TFs modulate the function of more ubiquitous TFs. Using single-cell RNA-seq data from the Tabula Sapiens atlas37, we calculated a tissue/cell type expression specificity score (TCESS) for TFs...
Various immune response parameters, such as mucosal fold, lamina propria, goblet cell and enterocytes resulting from dietary probiotic supplementation are presented in Fig. 1. Provision of probiotics through diet significantly (p < 0.05) increased the fattening of intestinal mucosal fold, width of lami...
It has now been shown that, in fission yeast, B-type cyclins also activate cdc2 in G1, thus governing cell-cycle commitment, as well as the onset of S phase. In this article, Karim Labib and Sergio Moreno review the evidence that ruml inhibits the kinase activity of cdc2 associated ...
Eukaryotic cells are used as cell factories to produce and secrete multitudes of recombinant pharmaceutical proteins, including several of the current top-selling drugs. Due to the essential role and complexity of the secretory pathway, improvement for r
Full size image The strong connection between the resealing of the yeast cell membrane and the wall recovery allows one to assume that this recovery process is “mechanical” in nature, which could be related to changes of osmotic pressure during electroporation and the processes taking place after...