cell size controlbudding yeastadderoptogeneticsPrecise control of cell size is evident across nearly all forms of life. Many cellular components, including DNA and organelles, display a strong positive correlation with cell size, and maintenance of uniform size may underlie the efficient functioning of...
Among all living organisms, there is almost much variety in cell size as there is for cell function and cell type. However, within each cell type, cells stay remarkably faithful to a defined size over generations. Many factors have been found to influence this ability to specify and maintain...
M. Cell size control in yeast. Curr. Biol. 22 (2012). Nasmyth, K. & Dirick, L. The role of SWI4 and SWI6 in the activity of G1 cyclins in yeast. Cell 66, 995–1013 (1991). Article CAS Google Scholar Ferrezuelo, F., Aldea, M. & Futcher, B. Bck2 is a phase-...
There is little consensus about the way mammalian cells control their size1,2. Studies of single-celled yeast and bacteria have revealed that in order to achieve size homeostasis, cells must modulate the amount of growth produced during the cell cycle such that, on average, large cells at birt...
6. Soifer, I., Robert, L., and Amir, A. (2016). Single-Cell Analysis of Growth in Budding Yeast and Bacteria Reveals a Common Size Regulation Strategy. Curr Biol 26, 356–361. 7. Cadart, C., et al. (2018). Size control in mammalian ...
Genetic control of cell size at cell division in yeast A temperature-sensitive mutant strain of the fission yeast Schizosaccharomyces pombe has been isolated which divides at half the size of the wild type. Stu... Nurse,Paul - 《Nature》 被引量: 1293发表: 1975年 Genetic control of the cell...
Interestingly, recent work in bacteria and in yeast implicates differential protein synthesis rates in cell size control (Basan et al., 2015, Schmoller et al., 2015). The latter study suggests that size control arises from differences in the size dependence of synthesis of a cell cycle ...
6. Soifer, I., Robert, L., and Amir, A. (2016). Single-Cell Analysis of Growth in Budding Yeast and Bacteria Reveals a Common Size Regulation Strategy. Curr Biol 26, 356–361. 7. Cadart, C., et al. (2018). Size control in mammalian cells involves modulation of both growth rate...
Sign in to download full-size image Figure 1.Yeast cell and its main organelles. The yeast cytoplasm is an aqueous, slightly acidic colloidal fluid that contains proteins, glycogen, other soluble macromolecules and larger macromolecular entities such as ribosomes,proteasomes, and lipid particles. Man...
In recent years, the field of automatic yeast cell detection has been revolutionized by the emergence of deep learning techniques, particularly convolutional neural networks (CNNs)10. These modern approaches leverage large amounts of labelled data to train highly complex models capable of directly lear...