prostateprostatic neoplasmsmice, transgenicdorsal proteinstransplantation, homologousComment on J Urol. 2004 Jan;171(1):439-42.doi:10.1097/01.ju.0000101708.01785.45TrueLawrenceElsevier Inc.Journal of UrologyTrue L (2004) Why we must better understand neuroendocrine differentia- tion in prostate cancer. J Urol 171(1): 443 - 444
There has been a recent expansion in our understanding of DNA-sensing mechanisms. Mitochondrial dysfunction, oxidative and proteostatic stresses, instability and impaired disposal of nucleoids cause the release of mitochondrial DNA (mtDNA) from the mitoc
Why is there more number of centrioles in cancer cells than in normal cells? Why are endothelial cells important? Why is cell culture important? Why are red blood cells considered cells? Why do eukaryote cells have telomeres? Why do cells go through cell differentiation? Why do cells need ...
Why are stem cells necessary for cell differentiation? Why are cells important to living things? Why are red blood cells considered cells? Why do cells have organelles? What does making new cells allow you to do? Why do some cells have microvilli?
Regulatory T cells, referred to as Treg for short, are a class of T cell functional subsets with important immunomodulatory functions and phenotypic characteristics of Foxp3, CD25, CD4, and other expression molecules. In 1995, Sakaguchi et al. [1] found that CD4+CD25+Treg subsets have importan...
In addition, the conditions in the cell culture are at least not improving the function of the cells [16]. The use of fresh, uncultured ADRCs instead of cul- tured ADSCs has two other important advantages for the patient: (1) as the cells are not cultivated in a laboratory, the ...
The glial cells of the primary olfactory nervous system, olfactory ensheathing cells (OECs), are unusual in that they rarely form tumors. Only 11 cases, all of which were benign, have been reported to date. In fact, the existence of OEC tumors has been d
cells undergo numerous cell divisions over their long lifespans, which creates additional opportunities for genetic mutations that could potentially lead to cancer. However, these large and/or long-lived wild animals tend to exhibit relatively low cancer incidence (PetoCitation2015; Tollis, Boddy, and...
Stem cells are possibly the most important bodily cell, being an undifferentiated, or unspecialised cell capable under certain circumstances of developing into any of the different cell types that make up the tissues and organs of the human body (“National Institutes of Health,” 2015). In the...
Thereafter, they are sustained by a combination of local division, differentiation from locally deposited precursors, and varying amounts of repopulation from bone marrow cells (or potentially other tissues) that differentiate in adult life. The contributions of these various pathways to ILC populations...