杨四军博士为著名糖尿病专家、留美八年,多年来一直从事外泌体调控线粒体自稳态在mtROS/NLRP3炎症小体激活级联效应在糖尿病发病中的作用与机制的分子研究。先后发表SCI论文20多篇,其中影响因子10分以上的5篇,发表的SCI文章总影响因子超150。获得国家自然科学基金重点项目子课题、国自然面上项目、教育部留学归国人员...
GenesCell differentiation, genes and cancer edited by T. Kakunaga ... [et al.] (IARC scientific publications, no. 92) International Agency for Research on Cancer, 1988doi:10.1136/jcp.42.11.1231-dNR LemoineInternational Agency For Research Oin CancerJournal of Clinical Pathology...
Cell death and Differentiation provides an accessible source of up-to-date information for scientists and clinicians. It covers programmed cell death, cell death induced by toxic agents, differentiation and their relation to cell proliferation.
Cellular differentiationis a generic term for the processes by which cells specialize phenotypically and morphologically to adapt to their environmental conditions or to perform specific functions [1]. This ability to generate specialized cell types from multipotent precursor cells is certainly central to ...
近日,Pan-Cancer Initiative发布了更大规模的基因组和分子数据的分析结果,涉及来自一万多名患者的33种不同的癌症。相关成果以27篇论文的形式发布在Cell、Cancer Cell、Cell Reports等杂志上。这是迄今为止最全面的跨癌症分析(cross-cancer analysis),也是癌症基因组图谱(The Cancer Genome Atlas)计划最终的成果。
题目:Non-coding RNAs and ferroptosis: potential implications for cancer therapy 译名:非编码RNA与铁死亡:对癌症治疗的潜在意义 期刊:Cell Death & Differentiation IF:15.828 发表时间:2022.4.14 通讯作者单位:格拉茨医科大学 DOI号:https:...
The p53 tumor-suppressor plays a critical role in the prevention of human cancer. In the absence of cellular stress, the p53 protein is maintained at low steady-state levels and exerts very little, if any, effect on cell fate. However, in response to var
Cell Death and Differentiation: 发表中国乳腺癌研究重要成果 2017年10月13日,英国《自然》旗下《细胞死亡与分化》在线发表中国科技大学、复旦大学附属肿瘤医院、厦门大学、中国科学院、安徽省立医院、安徽医科大学第一附属医院、密歇根大学综合癌症中心、复旦大学上海医学院和生物医学研究院的研究报告,发现通过阻断白细胞...
近日,安徽医科大学郑红团队在Cell Death & Differentiation杂志上在线发表了题为CCKBR+ cancer cells contribute to the intratumor heterogeneity of gastric cancer and confer sensitivity to FOXO inhibition的研究论文,揭示了CCKBR+的胃腺癌...
鳞状分化(Squamous differentiation) 鳞状细胞癌的独特特征是受影响分化的基因发生改变。多能性转录因子 SOX2 是位于 chr3q26 的 SCC 中的癌基因,在 27%的这些癌症中扩增。SOX2 在发育中起着关键作用,尤其是在细胞获得食道与肺的表型时。SOX2 对于 SOX2 获得性细胞的增殖是必需的。当与其他癌基因协同过表达时,SOX...