Cancer stem cells (CSCs) are asubpopulation of tumorcells that can drive tumor initiation and can cause relapses. At the time point of tumor initiation, CSCs originate from either differentiated cells or adult tissue resident stem cells. Can cancer stem cells be killed? A team of scientists ha...
which develop in a fixed, hierarchical order. Accordingly, such cancer stem cells are responsible for tumor progression and produce specific types of more differentiated cancer cells whose fates are predetermined.
SW48 cells, and SW1116 cells. These results suggest that the lack of growth inhibition by TGF-beta in SW48 and SW1116 colon cancer cells may be caused by a lack of expression of functional TGF-beta receptors. 展开 关键词: Humans Epithelium Tumor Cells, Cultured Colonic Neoplasms DNA, ...
D Beier,JB Schulz,CP Beier - 《Molecular Cancer》 被引量: 316发表: 2011年 Expression of MHC I and NK ligands on human CD133+ glioma cells: possible targets of immunotherapy Mounting evidence suggests that gliomas are comprised of differentiated tumor cells and brain tumor stem cells (BTSCs)...
MUC2+ differentiated colorectal cancer cells are predominantly ERBB3+.Thierry, JardéLisa, KassMargaret, StaplesHelen, LescesenPeter, CarneKaren, OlivaPaul, J. McMurrickHelen, E. Abud
1b). This conditioned media was transferred to naive differentiated C2C12 myotubes (Fig. 1a). Conditioned media from palmitate-treated C2C12 myotubes increased expression of UPR genes Atf4, Hspa5 and Edem1 (Fig. 1b). To determine the relevance of this phenotype in a human model, primary human...
Differentiated somatic mammalian cells putatively exhibit species-specific division limits that impede cancer but may constrain lifespans1,2,3. To provide immunity, transiently stimulated CD8+ T cells undergo unusually rapid bursts of numerous cell divisions, and then form quiescent long-lived memory cel...
Classified by cytopathology, cervical cancer cells: poorly differentiated, moderately differentiated, well differentiated, cell differentiation, the level of cervical cancer prognosis. 翻译结果2复制译文编辑译文朗读译文返回顶部 null 翻译结果3复制译文编辑译文朗读译文返回顶部 ...
8b). Regarding more differentiated progenitor cells, Lin−c-KitlowSca-1lowCD127+CD135+ (common lymphoid progenitors (CLPs)), Lin−c-Kit+Sca-1−CD34+CD16/32− (CD34+ common myeloid progenitors (CMPs)) and Lin−c-Kit+Sca-1−CD34−CD16/32− (bipotent megakaryocyte/erythrocyte...
Keywords: colorectal cancer; colon cancer; rectal cancer 1. Introduction Colon cancer (CC) and rectal cancer (RC) are regarded in all fields of research and clinical practice a single tumor entity termed colorectal cancer (CRC). This is based on the assumption that CC and RC develop in the...