MUC2+ differentiated colorectal cancer cells are predominantly ERBB3+.Thierry, JardéLisa, KassMargaret, StaplesHelen, LescesenPeter, CarneKaren, OlivaPaul, J. McMurrickHelen, E. Abud
How regular cells are similar to cancer cells?Cells:Cells are the smallest unit of life. Cells can be eukaryotic, meaning they possess true nuclei and membrane-enclosed organelles. They can also be prokaryotic, meaning they lack both of these features and only have a nucleus-like region called...
Naïve cells can still differentiate into another type of T or B effector cell. Many effector cells are considered “terminally differentiated,” meaning they will never change into another cell type and have reached the end of their differentiation and maturation process. They are fully activated ...
Entrena5,6, Carmen Griñán-Lisón1,2, Margarita Aguilera2,7, Manuel Picon-Ruiz1,2,8 & Juan A. Marchal1,2,3 Cancer stem cells are responsible for tumor progression, metastasis, therapy resistance and cancer recurrence, doing their identification and isolation of special ...
1b). This conditioned media was transferred to naive differentiated C2C12 myotubes (Fig. 1a). Conditioned media from palmitate-treated C2C12 myotubes increased expression of UPR genes Atf4, Hspa5 and Edem1 (Fig. 1b). To determine the relevance of this phenotype in a human model, primary human...
normally are closed off to mature melanocytes (the cells that make melanin and give skin its color). In order to access these locked-up genes, the cells require specific proteins that act as keys. Without them, the cells do not form melanoma, even when they have cancer-associated DNA ...
Importantly, FISH analysis of differentiated ependymoma cells confirmed that these are cancer cells and not normal cells (Figure 5O). Thus, ependymomas contain a rare fraction of RGC-like cancer cells that display the stem cell properties of self-renewal and multipotency. Download: Download high-...
Abstract 5327: Glioma derived cancer stem cells are hypersensitive to proteasomal inhibition Cancer ResearchY. D. Yoo, D. H. Lee, H. Cha-Molstad et al., "Glioma-derived cancer stem cells are hypersensitive to proteasomal inhibi- tion," ... DH Lee,CO Sang,TK Yong,... - 《Cancer Researc...
2005. Dendritic cells differentiated in the pres- ence of IFN- and IL-3 are potent inducers of an antigen-specific CD8ϩ T cell response. J. Leukocyte Biol. 78: 898 -908.Breckpot K, Corthals J, Bonehill A, Michiels A, Tuyaerts S, Aerts C, Heirman C, Thielemans K. ...
Differentiated somatic mammalian cells putatively exhibit species-specific division limits that impede cancer but may constrain lifespans1,2,3. To provide immunity, transiently stimulated CD8+ T cells undergo unusually rapid bursts of numerous cell divisions, and then form quiescent long-lived memory cel...