Whole-genome sequencingWhole-exome sequencingNext-generation sequencingAcute leukemiaAcute myeloid leukemiaAcute lymphoblastic leukemiaAcute leukemia is characterized by abnormal proliferation of hematopoietic cells. Development of new technologies, including whole-genome sequencing (WGS) and whole-exome sequencing...
This economic evaluation estimates the cost-effectiveness of whole-genome sequencing compared with whole-exome sequencing and conventional testing in
Based on workflow, the global whole genome and exome market was led by the WES segment, which held a 64.92% share in 2023. The whole exome sequencing (WES) workflow begins with the extraction, isolation, and p...
Zhiming Cai and colleagues report whole-genome and whole-exome sequencing of 99 paired tumor-normal samples of transitional cell carcinoma of the bladder. They find that 32% of tumors harbor alterations in genes involved in sister chromatid cohesion, inc
Analysis and Annotation of Whole-Genome or Whole-Exome Sequencing-Derived Variants for Clinical Diagnosis. 2013:, 9.24.1-9.24.24. /Worthey, E.A., 2013. Analysis and annotation of whole-genome or whole-exome sequencing-derived variants for clinical diagnosis. Curr. Protoc. Hum. Genet. 79 (...
Can I analyze VCF data for my whole exome/whole genome sequence analysis project? Yes, you can analyze both raw sequencing data as well as VCF variant data for genome resequencing projects in Lasergene. When starting from VCF data, Lasergene will classify called variants by their effect on ...
Research of these determinants has been performed in candidate gene, genome-wide association and linkage studies. Because exploration of the common variation in the genome did not explain much of the variation in the rate of aging and longevity, researchers in the field have only recently started ...
Whole exome sequencing is a powerful tool to investigate genetic variations underlying cancers, Mendelian diseases, and complex human disorders.
Exome sequencing is a targeted sequencing approach that is restricted to the protein-coding regions of genomes. The exome is estimated to encompass approximately 1% of the genome, yet contains approximately 85% of disease-causing mutations [1]. For genetic re...
Whole genome sequencing (WGS) vs. Whole exome sequencing (WES) Whole genome sequencing (WGS) is used to determine the order of every single nucleotide in an individual’s genome. This is a powerful way to uncover genomic variation, including disease-associated mutations. However, sequencing ent...