Whole exome sequencing of wild-derived inbred strains of mice improves power to link phenotype and genotype. Mamm Genome. 2017;28:416–25. Article CAS PubMed PubMed Central Google Scholar Geiger M, Sanchez-Villagra MR, Lindholm AK. A longitudinal study of phenotypic changes in early ...
WES: Whole-exome sequencing WGS: Whole-genome sequencing References Naghavi M, Abajobir AA, Abbafati C, Abbas KM, Abd-Allah F, Abera SF, et al. Global, regional, and national age-sex specific mortality for 264 causes of death, 1980–2016: a systematic analysis for the Global Burden ...
Whole-exome sequencing focuses on what is thought to be the most medically relevant part of the human genome, as this reduces the overhead of both the molecular and analytical aspects. This approach has been broadly applied to identifying the genes that underlie rare disorders. In only the pas...
Exome capture, sequencing, and bioinformatic analysis Picard MarkDuplicates software estimated rates of PCR duplication to be very high, ranging from 83.3 to 96.7% of uniquely aligned reads (Supplementary Table S1). As a result, coverage of targeted bases following duplicate removal was very low (...
Use of Whole-Exome Sequencing for the Diagnosis of Atypical Birte-Hogge-Dubé Syndrome非典型外显子综合征测序诊断断层扫描遗传性疾病高解析度Destruction of the lung parenchyma may result in the formation of cysts,cavities and bullae.Definition of the type of destructive lesion is best achieved by ...
Since a minor allele frequency (MAF) of 1% or more is the conventional definition of polymorphism84, thus we considered a MAF < 1% as ‘rare variation’. We tested whether any of the genes identified by exome sequencing had statistical evidence of association with SLE in the general Eur...
Methods. Several studies showed that whole exome sequencing (WES), as well as RNA-seq, can identify pathogens, particularly viruses, in cancer clones enabling the definition of possible integration sites in the host genome or their presence as episomal forms. In the present study, we searched ...
Define whole gale. whole gale synonyms, whole gale pronunciation, whole gale translation, English dictionary definition of whole gale. n. See storm. American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton
Whole Exome Sequencing Market by Product [Systems, Kits (Library Preparation, Target Enrichment)], Services (Sequencing), Technology (Sequencing by Synthesis), & by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 Description TABLE OF Contents METHODOLOGY Download PDF Whole ...
UseofWhole—ExomeSequencingfortheDiagnosisofAtypical Birt-Hogg-Dub6Syndrome Destructionofthelungparenchymamayresultintheforma— tionofcysts,cavitiesandbullae.Definitionofthetypeof destructive 1esion is best achieved by high—resolution computedtomography(HRCT)scansofthechest(Trotman— ...