Notably, a recently determined crystal structure of SARS-CoV-2 capsid has revealed its close similarity to that of SARS-CoV-1 and MERS-CoV. Capsid symmetry greatly contributes to virion stability and balance between genome. Enveloped icosahedral viruses are very common in animals, and rare in pla...
Variant hunting, as exciting as that sounds, is performed through whole genome sequencing of samples that have tested positive for the virus. This process involves checking every sequence obtained for differences compared to what we know is circulating in South Africa and the world. When we see m...
1a). The successful infection by SARS-CoV-2 occurs through recognition of receptor on the surface of target cell, binding of S protein to the receptor, anchoring the viral envelope to the target cell, and ultimately the viral genome internalization (Plemper, 2011) (Fig. 1b, c). During ...
Accordingly, the first key take-away of this review is to incorporate change from the creation of the treatment plan for the patient: looking beyond hyperglycemia. Large-scale studies in type 2 diabetes patients have proven to be a treasure-trove for insights into the nature and management of ...
So again, I don’t have evidence for that, but I do have evidence that [SARS-CoV-2] is an artificially-made bioweapon. So why wouldn’t it be possible to make variants the same way? I think it’s kind of a combination, multifactorial cause of variants — the natural God factor, th...
According to biomedicinem all diseases are caused by either a bacterium, a virus, poison, a prion — a prion is a piece of protein — or today, since the human genome project of genomics, a piece of the effective gene through you, right? So your illness is caused by one of these ...
I basically only saw retrosynthesis so far.) or solving OT problems as in DSBM that does so for fluid flow downscaling. Maybe a lot of tools emerged in 2023 (also let us mention BM with multiple marginals), and in 2024, the community will make good use of them? Joey...
The COVID-19 pandemic has infected nearly 178 million people and claimed the lives of over 3.8 million in less than 15 months. This has prompted a flurry of research studies into the mechanisms and effects of SARS-CoV-2 viral infection in humans. However, studies examining the effects of CO...
The infection caused by SARS-CoV-2 virus initially targets key areas of the lungs and airways that usually allow the transfer of oxygen into the blood circulation [47,48]. Affected individuals with pre-existing chronic medical conditions, such as heart disease and diabetes, are considered to be...
Mutation of SARS-CoV-2 Coronavirus Mutations viral evolution pathogen features World Health Organization: WHO and its global group of specialists is actively watching mutations in the virus so, if major modifications are discovered, WHO can advise governments and people on how to alter their efforts...