tuberculosisBedaquiline and delamanid used to treat extensively drug-resistant tuberculosis are known to cause prolonged QTc. Two children with extensively drug-resistant tuberculosis were put on bedaquiline and delamanid and had prolonged QTc on the Bazett formula but normal QTc by the Fridericia formula...
As a manufacturer of electrocardiographs with a computerized interpretation program, we hear conflicting comments regarding the "Prolonged QT" statement in the interpretation, ranging from "too many ECGs say Prolonged QT" to "how could it not say Prolonged QT when the QTc is over 500 msec?" ...
Bedaquiline and Delamanid in Children With XDR Tuberculosis: What is prolonged QTc? Bedaquiline and delamanid used to treat extensively drug-resistant tuberculosis are known to cause prolonged QTc. Two children with extensively drug-resist... I Shah,S Gandhi,NS Shetty - 《Pediatric Infectious Disease...
Hospitalized patients have a high prevalence of prolonged QTc and are a high-risk population for Torsades de Pointes (TdP). One modifiable risk factor for ... C Dora,P Jonathan,H Gary,... - 《Journal of the American Medical Informatics Association》 被引量: 0发表: 2018年 Chapter 4: chil...
If the patient has a prolonged QTc at baseline (>450 ms in men and >460 ms in women in the absence of interventricular conduction defects), it is important to try to avoid all QT-prolonging medications.47 Although this is not an absolute contraindication to starting QT-prolonging drugs, ...
Background: Prolonged QTc (corrected QT) interval and torsades de pointes (TDP) are associated withhypocalcemia, hypomagnesemia, hypokalemia, possibly alkalosis and may result in syncope and sudden cardiac death. Do you do CPR for torsades?
We still do not know why QT interval is prolonged and how this abnormality leads to death. Nevertheless, QT interval is a simple, low-cost measure, ... M Veglio,A Chinaglia,P Cavallo-Perin - 《Journal of Endocrinological Investigation》 被引量: 229发表: 2004年 QT prolongation modifies dyna...
(0.26 sec) compared with the PR intervals of the other sinus complexes. Because every third QRS complex is a PVC, this is ventricular trigeminy. The QT/QTc intervals are normal (400/400 msec and 360/360 msec when the prolonged QRS complex duration is considered)....
2. Cytochrome P450 enzyme inhibitors such as cimetidine have minimal impact on the plasma concentration of Tropisetron hydrochloride, and no dose adjustment is required under normal use. 3. Clinically insignificant QTc prolongation has been observed in patients receiving intravenous high doses (80 mg)...
The latter two also carry boxed warnings for cardiopulmonary arrest/sudden death and are associated with hypomagnesemia (electrolytes should be monitored) but not QTc prolongation [63, 64]. The anti-CD22, moxetumomab pasudotox, has a boxed warning for capillary leak syndrome (CLS), a rare ...