Transcription is the creation of a strand of mRNA from a DNA template, carrying the same instructions (i.e., genetic code) for making a particular protein as the template does. The process occurs in the cell nucleus, where DNA is located. When a double-stranded DNA molecule separates into ...
Acetylation Reaction | Definition, Mechanism & Examples from Chapter 3 / Lesson 20 35K Learn the definition of acetylation, how the acetylation reaction occurs, and about lysine acetylation. See the mechanisms and examples of acetylation reaction. Related...
Transcription factor binding in human cells occurs in dense clusters formed around cohesin anchor sites. Cell 154, 801–813 (2013). Defines a potential role for cohesin in marking sites of transcription factor binding for reassociation after replication and mitosis. CAS PubMed Google Scholar Strub...
This repression occurs through BRD8-dependent maintenance of H2A.Z occupancy at p53 target loci, leading to a repressive chromatin state and facilitating the sustained proliferation of these cancer cells. The reason why H2A.Z functions as a repressor in this context remains unclear. Recently, ...
The determination of the sex of a human occurs at conception. Explore how sex is determined, X-inactivation, and how Barr bodies play a role in sex determination. Related to this Question What is genomic imprinting? What is the role of DNA gyrase?
occurs in renal cells after kidney injury [31]. Renal fibroblasts and tubular epithelial cells (TECs) are the main cell types that undergo metabolic reprogramming during renal fibrosis [32]. Reprogramming of lipid, glucose, and AA metabolism occurs in CKD, affecting the function and survival ...
It has been shown that the same effect occurs in the visual system [27]. Mice were monocularly deprived for a couple of days early in life so that the visual system adapted to this change of the visual environment. Subsequently, animals were subjected to normal vision again so that their ...
To produce the pyrophosphate molecule necessary for phosphorous spin entanglement, two phosphate groups should be detached during ATP hydrolysis instead of a single one in the usual ATP-ADP cycle. This double phosphate group detachment occurs in the synthesis of cAMP (cyclic AMP) from ATP by ...
In human oncology, a correlation between the amount of sex hormones and the development of lymphoma has been observed for years [28,29]. It is suggested that female sex hormones (estrogens and progesterone) may protect against NHL, as it occurs less frequently in women than in men, and its...
Histone acetylation occurs by the enzymatic addition of an acetyl group (COCH3) from acetyl coenzyme A. The process of histone acetylation is tightly involved in the regulation of many cellular processes includingchromatindynamics and transcription, gene silencing, cell cycle progression, apoptosis, diff...