What are the factors that make a good nucleophile? For our purposes, there are at least four key factors contributing to nucleophilicity. Charge Electronegativity Solvent Steric hindrance The first two should hopefully be familiar from the discussion of what makes something a strong base. After all...
Learn about what compounds are soluble in water, and review examples. Understand what is special about water as a compound and what makes something soluble in water. Related to this QuestionWhy is benzene less reactive than 1,3,5-cyclohexatriene? Explain the important points regarding the molecu...
Something similar has been proposed for the T-segment passage through the DNA-gate of type IIA DNA gyrase, except that the residues interacting with the DNA are well-conserved in this case [84]. In addition, some topoisomerases have loops inserted at different positions in the domain DII ...