HeLa cells refer to a line of cells belonging to a strain that has been continuously cultured since 1951 and were the only cells to survive in vitro.
By studying the 3-D structure of AIF, the team first identified the molecular pocket that looked like a potential PAR binding site. They then swapped that region out for a different one to see if it indeed took up PAR. Using HeLa cells in addition to mouse nerve and skin cells, the sc...
gold nanoparticles with “special” surface chemistries/arrangements can enter cells by direct penetration. Verma et al. (2008) showed that gold nanospheres (~5 nm) decorated with two capping molecules (anionic and hydrophobic, with alternating positions on the surface...
HeLa cells are immortal cells having error-filled genomes, while normal cells are non-immortal cells having normal genomes. Thus, this is the key difference between HeLa cells and normal cells. HeLa cells contain 76 to 80 total chromosomes per cell, while normal cells contain 46 total chromosome...
in the human body. Benign cancer cells do not invade nearby tissues. But canceroustumorscan travel to distant places in the body to form new tumors. Cancer cells have been described as immortal as they don’t age or die. HeLa cells and cancer cells are two types of immortal cells. ...
Infection of Hela cells or mouse embryonic fibroblasts (MEFs) with MVA resulted in the upregulation of dual specificity phosphatase 1 (DUSP1), a MAPK dephosphorylating enzyme [192]. Infection of DUSP1 knockout mice with MVA enhanced the production of pro-inflammatory cytokines indicating that DU...
A brief review of the history of cancer research makes one wonder if modern strategies for treating patients with solid tumors may sometimes cause more harm than benefit. Keywords: cancer therapy; intratumor heterogeneity; polyploid giant cancer cells; senescence; apoptosis; anastasis; immune system; ...