Subcutaneous unfractionated heparin (UH) has become the treatment of choice due to its safety and ease of monitoring and administration. Patients who are commonly treated include any acutely ill patient confined to bed, such as one with heart failure, respiratory disease, and postoperative care. ...
The current standard of care for anti-thrombotic therapy with primary PCI for acute ST elevation myocardial infarction (STEMI) is aspirin, clopidogrel, unfractionated heparin and platelet glycoprotein IIb/IIIa inhibitors. However, heparin and glycoprotein IIb/IIIa inhibitors are associated with a high ...
The American College of Chest Physicians recommends therapeutic doses of intravenous unfractionated heparin, low-molecular-weight heparin, or fondaparinux for initial treatment of UEVT, followed by at least 3 months of treatment with a vitamin K antagonist. Q/ What's the best way to manage upper...
There is no question that Lovenox can lead to more perioperative bleeding and lower postoperative hemoglobins. Wound drainage must be managed aggressively, even if it means stopping physical therapy for several days until the wound seals. If it continues 7 to 10 days, irrigation and debridement sh...
The benefit of bivalirudin in reduction of major bleeding compared with unfractionated heparin in percutaneous coronary intervention remains a matter of on-going debate. Multiple metaanalyses had illustrated a substantial reduction in the risk of major bleeding with bivalirudin [1,2,3]. However, we ...
Dose after 5–10 days of initial therapy with a parenteral anticoagulant Dabigatran 150 mg po BID; 110 mg BID for patients ≥80 years old – Reduce dose to 110 mg BID for patients ≥80 years or ≥75 years with at least one bleeding risk factor. UFH: unfractionated heparin; subQ: subcuta...
The TETAMI Trial: The Safety and Efficacy of Subcutaneous Enoxaparin versus Intravenous Unfractionated Heparin and of Tirofiban versus Placebo in the Treat... Patients with acute myocardial infarction (AMI) who do not receive early reperfusion therapy are at high risk of reinfarction or death, and...
Among the key recommendations in this chapter are the following: In children with first episode of venous thromboembolism (VTE), we recommend anticoagulant therapy with either unfractionated beparin (UFH) or low-molecular-weight heparin (LMWH) [Grade 1B]. Dosing of IV UFH should prolong the ...
Safety and efficacy of enoxaparin compared with unfractionated heparin and oral anticoagulants for prevention of thromboembolic complications in cardiovers... INTRODUCTION: Anticoagulation in cardioversion for atrial fibrillation is performed using unfractionated heparin and oral anticoagulants. TEE-guided cardio....
Neuraxial anesthetic techniques are commonly used during the peripartum period to provide effective pain relief for labor and anesthesia during cesarean delivery. Major neurologic complications are rare after neuraxial anesthesia; however, spinal hematom