Arjomand H,Surabhi SK,Cohen M.Unfractionated versus fractionated heparin for percutaneous coronary intervention.Curr Cardiol Rep. 2002Heidar Arjomand MD,Satish K. Surabhi MD,Marc Cohen MD, FACC.Unfractionated versus fractionated heparin for percutaneous coronary intervention[J]. Current Cardiology Reports ....
Unfractionated heparin administration in patients treated with bivalirudin during primary percutaneous coronary intervention is associated lower mortality and target lesion thrombosis: a report from the SCAAR registry. Heart 2011;97:484-8.Koutouzis M, Lagerqvist B, James S, et al. Un- fractionated ...
Objective To compare the clinical efficacy and influence on blood coagulation between low molecular weight heparin( LMWH) and unfractionated heparin( UFH) in the adjuvant treatment of elderly patients with severe pneumonia( SP). Methods 105 elderly SP cases were randomly divided into the LMWH group ...
Objective To investigate the effect of low molecular weight heparin on lipid parameters in hemodialysis patients. Methods The trial was double blind, open, controlled and randomized for one year. 35 pre-dialysis patients were divided into two groups: UFH(unfractionated heparin) group(n = 13) and...
Importantly, we also demonstrated that side-fractions can be sub-fractionated by AEC (Fig.2), indicating heterogeneity of these HS by-products as observed previously in HS samples purified from raw Hp4. The patterns of separation by AEC clearly demonstrated that each fraction is distinct from eac...
(UFH) LesslikelytocauseHITAbformation LesslikelytocauseHITinpatientswho haveformedHITAbs LMWHvsUFH LowMolecularWeightHeparinUnfractionatedHeparin •preparedby chemical/enzymatic depolymerizationofUFH •~5000Da •morepotentagainstFXa thanIIa •Administered subcutaneously •Derivedfrombovinelungor porcinegut ...
Heparin binds reversibly to its target sites of action, antithrombin and the other serine proteases involved in coagulation, especially activated factor X. It also binds to other plasma proteins, including fibrinogen, plasmin, albumin, and Upases. The volume of distribution of heparin is then, unde...
16.The method of claim 15, wherein the heparin is heparin fragment, low-molecular-weight heparin or unfractionated heparin. 17.The method of claim 14, wherein the isolated antibody or antigen-binding fragment thereof is administered with a heparin mimic. ...
In some embodiments, the heparin is low-molecular-weight heparin or unfractionated heparin. In some embodiments, a heparin mimic is being or has been administered to the subject. In some embodiments, the heparin mimic is fondaparinux. In some embodiments, HIT has been diagnosed in the subject ac...
There were 35 further cancer deaths (11 low molecular weight heparin group, 24 unfractionated heparin group) and 23 patients with late onset thromboembolic complications (11 low molecular weight heparin group, 12 un fractionated heparin group). The two drugs were of similar efficacy but the ...