but prolonged high concentrations may cause ototoxicity and nephrotoxicity. Peak plasma concentrations of 6 to 10 mg/L and trough concentrations of less than
The analysis also found that, in addition to KaiA, KaiB and KaiC, the test tube also contained large amounts of the three smaller molecules, called monomers, that are the basic building blocks for the bioclock proteins. KaiC is a hexamer that is made up of six monomers. KaiA is a dimer...