Marker molecules, also known as molecular markers or genetic markers, are used to mark the position of a specific gene under investigation, or draw attention to the inheritance of a characteristic. They have proven an essential tool for geneticists and have found essential applications in genetic e...
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A Sex-linked Microsatellite Marker Reveals Male Heterogamety in Quasipaa boulengeri(Anura: Dicroglossidae) Few amphibians possess morphologically distinguishable heteromorphic sex chromosomes.The classic indirect method is a time-consuming and resource-demanding... S Yuan,Y Xia,X Zeng - 《亚洲两栖...
Gastric intestinal metaplasia occurs as a pathological condition in the gastric mucosa. To clarify how an intestine-specific homeobox gene, Cdx2, affects the morphogenesis of gastric mucosa, we generated transgenic mice expressing Cdx2 in parietal cells. Until Day 18 after birth, the number of ...
The transcriptional factor LBP-1c/CP2/LSF gene on chromosome 12 is a genetic determinant of Alzheimer's disease Although the varepsilon4 allele of the apolipoprotein E gene appears as an important biological marker for Alzheimer's disease (AD) susceptibility, other g... Lambert Jean-Charles,G...
Human Gene Marker/Therapy Clinical Protocols (Complete Updated Listings)[J].Human Gene Therapy, 2000; 11(18)1 2543 Lehrman S. Virus treatment questioned after gene therapy death.Nature. 1999 Oct 7;401(6753):517-8. DOI: 10.1038/43977. PMID: 10524611. ...
meaning that different forms of the gene coded by the marker exist in different organisms of the same species and result in some form of change in the organisms. In general, there is little information to be gained from non-polymorphic sites. Also, polymorphisms lead to visible changes, such...
(CTLA-4) on the surface of Treg cells, and there is a linear correlation between them [28,29]. Mutations of Foxp3 gene can hinder the development of Tregs and lead to a fatal multi-organ autoimmune disease which is called X-linked polyendocrinopathy enteropathy with immune dysregulation ...
(Fig.4. In this approach, CBE edits a marker gene, such as acetolactate synthase (ALS), conferring herbicide resistance to the edited cells, while Cas12a/crRNA targets the gene of interest. The construct is delivered through transientAgrobacterium-mediated expression. ALS-edited transformants are ...
16S rRNA sequencing primarily utilizes PCR to amplify the specific gene region of interest (V4, V9, etc) that is then templated for NGS, thus only 16S gene sequences are generated. This is contrary to shotgun metagenomics, in which the entirety of genomic content is templated for NGS, thus...