Elsner M, Terbish T, Jörns A, Naujok O, Wedekind D, Hedrich HJ, Lenzen S.Reversal of diabetes through gene therapy of diabetic rats by hepatic insulin expression via lentiviral transduction.Mol Ther. 2012 May;20(5):918-26. doi:10.1038/mt.2012.8 Peeters M, D'Arc M, Delaporte E.Orig...
the key strategic insight that characterizes successful programs is the choice of a disease target where current gene therapy can deliver a therapeutic outcome. A thorough understanding of the disease, the vector and its delivery, and requisite levels of transgene expression are necessary...
Identification of the molecular components responsible for these processes is tied strongly to our knowledge of neurotrophic factors, their cognate receptors, and associated signal transduction pathways. Neurotrophic factors (e.g. nerve growth factor, brain-derived growth factor, glial cell line-derived ...
65 Briefly, canine ECFCs were transduced using lentiviral vectors containing the human VWF cDNA. One day after transduction, cells indeed expressed functional multimerized VWF at levels threefold higher compared with normal ECFCs. However, expression levels decreased sevenfold over a 4-week period ...
Looking for online definition of CHABC or what CHABC stands for? CHABC is listed in the World's most authoritative dictionary of abbreviations and acronyms
Virella-Lowell I, Poirier A, Chesnut KA, Brantly M, Flotte TR (2000) Inhibition of recombinant adeno-associated virus (rAAV) transduction by bronchial secretions from cystic fibrosis patients. Gene Ther 7:1783–1789 CrossRef Zabner J, Couture LA, Gregory RJ et al (1993) Adenovirus-mediated...
Coated bristol stock is a popular choice for common print jobs such as brochures, pamphlets and flyers, annual reports, greeting cards and directories. It is run to thickness and is available in sheets that are coated one-side or two-side. All too frequently when selecting paper, instant and...