The formal assessment of What Matters for older adults is often done in a medical setting through the acquisition of legal forms to prepare for end-of-life care. For many indigenous elders, however, these forms may appear impersonal or culturally insensitive. What Matters should go beyond end-...
NHEJ. However, NHEJ is error-prone, and it usually results in insertions and deletions (indels) in the region being repaired. When indels occur within the coding region of a gene and result in a frameshift mutation, the gene becomes non-functional. This is known as a gene knockout (KO)...
using NVivo and printed-out transcripts, involving regular meetings to discuss the emergent themes. This study is constrained by some methodological limitations and, particularly, by issues related to sampling and scope, as these were greatly influenced by the effect of the COVID-19 pandemic on ...
Discussed here is evidence for the roles of ABC and SLC transporters in the handling of diverse substrates, including metabolites, antioxidants, signalling molecules, hormones, nutrients and neurotransmitters. It is suggested that these transporters may be part of a larger system of remote communication...
Harm Reduct J (2021) 18:64 https://doi.org/10.1186/s12954-021-00508-1 RESEARCH Open Access "You know, we can change the services to suit the circumstances of what is happening in the world": a rapid case study of the COVID‑19 response across city centre homelessness and...
We’ll compare straightforward coding approaches and LLM-assisted options and discuss reliability, open-source implications, and the security angle (who would you trust to click and execute commands on your system?). By the end, you’ll have practical insights into deciding when an agent is the...
Despite recent major advances in developing effective vaccines against toxoplasmosis, finding new protective vaccination strategies remains a challenging and elusive goal as it is critical to prevent the disease. Over the past few years, various experimental approaches have shown that developing an effectiv...
What is recombinant DNA technology? What if all the DNA turned into RNA? Which of these is/are features of Sanger DNA sequencing but not in vivo DNA replication in eukaryotes? (a) The use of DNA primers. (b) The use of deoxynucleotides. (c) The use of dideoxynucleotides. (d) The ...
Epigenetic memory is defined as the maintenance of gene expression states through cell generations in the absence of the initiating signals. PREs were first discovered in flies, in which they can mediate epigenetic memory of both silent and active states of their associated genes. Epigenetic memory ...
In the world of smartphones, 1440p displays are sometimes marketed as "Quad HD"(QHD), as it is four times the resolution of 720p high definition(HD). The Vivo Xplay 3S, released in December 2013, was the first smartphone using a 1440p display. In the year of 2014, a large number...