There is now a growing awareness that the main limitations in understanding and successfully treating GBM might be bypassed by the identification of a distinct cell type that has defining properties of somatic stem cells, as well as cancer-initiating capacity - brain tumor stem cells, which could...
There is now a growing awareness that the main limitations in understanding and successfully treating \{GBM\} might be bypassed by the identification of a distinct cell type that has defining properties of somatic stem cells, as well as cancer-initiating capacity — brain tumor stem cells, which...
Cav3.2 activation (by RF-EMF) induced p38 MAPK phosphorylation Metastatic breast cancer cells 65 AKT Mibefradil (10 µM) reduced AKT phosphorylation at Ser473; Cav3.1 gene silencing reduced AKT phosphorylation at Ser473 GBM cell lines 75 Mibefradil (10 µM) reduced AKT phosphorylation at Ser...
Glioblastoma (GBM) is the most frequent and aggressive malignant primary central nervous system tumor in adults [...]
ATGBM ATGC ATge ATGF ATGI ATGiB ATGIS ATGK ATGL ATGLANT ATGLS ATGM ATGM/ADS ATGN ATGNI ATGO ATGP ATGPAC ATGPNW ATGRC ATGS ATGSB ATGSP ATGTF ATGV ATGW ATGWP ATGWS ATGWU Ath ATH-LOG ATH1 ATHA ATHAG ATHAM ATHC ATHCM ...
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The radar guns are always aimed at the pitcher and I believe the locations of the tumors indicate the radar is the trigger. For example, catchers would get the cancer on the back of the head or the brain stem and the pitchers would get the cancer in one of the temporal lob...
However, as postulated by Hanahan and Weinberg, cancer is not simply constituted by proliferating cancer cells but it consists of different cell types involved in heterotypic interactions [27,29]. Importantly, this tumour-associated stroma is not an inert witness but it plays an active role in tu...
Despite these regimens, prognosis remains poor.1 Various biomarkers are used to predict prognosis of patients with GBM.2 Amongst these, methylation of O6-methylguanine-DNA methyltransferase (MGMT) is considered to be a biomarker for good prognosis.3,4 MGMT is a DNA repair protein, that repairs ...
Therapeutics (OTCBB: IMUC) today announced that clinical data on ICT-107, the company's lead cancer stem cell-targeting vaccine for the treatment of glioblastoma multiforme (GBM), were presented in two oral sessions at the World Stem Cell Summit, which is being held October 4-6 in Detroit,...