Drug tolerance to target therapy in melanoma revealed at single cell level: What next? - ScienceDirectDrug resistanceMelanomaTumor heterogeneityDrug resistance strongly impairs the efficacy of virtually every kind of anticancer therapy. This phenomenon is commonly fueled by intrinsic or acquired mechanisms...
When drug taking is repeated beyond prescribed usage, it often leads to a pattern of drug dependence and tolerance. Tolerance is the body's need for larger or more frequent doses of a substance to achieve the same effect. It occurs when the body has learned to tolerate, or become used to...
All of these effects relate to taking a small amount of heroin, depending on the tolerance level of the user.所有这些影响都与服用海洛因有关,同时还会依据使用者成瘾程度变化。An addict will have a much higher tolerance and need more of the drug to feel the same effect.上瘾者会对海洛因有更高...
Drug use is often referred to as a steep slope, where one or two encounters can lead to dependence. In this lesson, learn about how this slope can steepen through the development of drug tolerance, which can lead to overdose and a host of other problems. Related...
WhatdrugwhatDrug 系统标签: drugaddictiontemperanceprohibitionsubstancetreatment 1ConceptualModelsofSubstanceUse•Differentcausalfactorsemphasized•Differentinterventionsbasedonconceptualmodels2MoralModelAddictionisaconditionforwhichanindividualispersonallyresponsible.Thepersonhascompleteself-control,andcanchoosetodothe“right...
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They also build a tolerance to the drug from frequent use, which places them at a higher risk of overdosing. In contrast, first time users may overestimate the amount of drug their body can handle, resulting in toxicity. Hot temperatures may be a risk factor when drugs such as cocaine or...
This lesson is going to define acute toxicity. Then you'll learn about the numerous kinds of signs and symptoms that may develop with an acute...
A blockbuster drug is a medication with annual sales of over $1 billion, but when patents expire, much of that revenue dries up.
Drug detox will be different for everyone. The more you know about the process, the better you can prepare to make your experience as smooth as possible.