Drug Vehicle A carrier or inertmediumused as asolvent(ordiluent) in which a medicinally active agent is formulated and oradministered.(NCI Thesaurus)
In this mini-review, focusing on BRAF-mutated melanoma as prototypical example, we analyze how recent studies that make use of single cell analysis identify the involvement of distinct transcriptional trajectories as the common thread at the basis of drug tolerance. The identification of these ...
With the loss of a succession of organ functions as we age,it is inevitable that we will suffer from various diseases,of varying severity,leading to our death.In fact,we do not die from a specific disease;we die from ageing itself—from the exhaustion of vital forces,from the unavoidable ...
What Does Brick-and-Mortar Mean? Bankruptcy: Definition & When To File What Is a Bear Market and How Should You Invest in One? Intro to Behavioral Finance What Are Bond Funds? What Is a Bull Market? What Does Bag Holder Mean? What Is a Buy & Hold Strategy in Investing? What Does It...
that involves damage to connective tissue (tendons, ligaments, cartilage, fascia, etc.) throughout the body, damage to the nervous systems (central, peripheral and autonomic), and more. Even though I knew why I was sick, I was still left wondering, what does fluoroquinolone toxicity mean?
Tolerance Diminution in the physiological response to a drug that occurs after continued use, necessitating larger doses to produce a given response. Allowance Acknowledgment. Tolerance The ability to digest or metabolize a food, drug, or other substance or compound Glucose tolerance. Allowance An amo...
Determine Optimal Threshold – The threshold for unacceptable failure can be determined based on a cost function assuming each breakthrough run is equivalent to the cost of not utilizing a set number of resin cycles. The cost function used can be customizab...
When drug taking is repeated beyond prescribed usage, it often leads to a pattern of drug dependence and tolerance. Tolerance is the body's need for larger or more frequent doses of a substance to achieve the same effect. It occurs when the body has learned to tolerate, or become used to...
Regardless of a person’s tolerance, alcohol exerts its influence when the amount of alcohol taken in exceeds the amount that the body can digest. At that point, alcohol passes from the bloodstream into the brain and begins its attack. Alcohol first affects the brain’s cortex, which controls...
Question: What does it mean if one can 'manually or consciously control' their own metabolism? Metabolism: Metabolism is the physiological mechanism by which the ingested food is digested and converted into energy that the body can use. This conversion process is achieved through ...