What is UPLIZNA? UPLIZNA is a prescription medicine used to treat adults with neuromyelitis optica spectrum disorder (NMOSD) who are anti-aquaporin-4 (AQP4) antibody positive. It is not known if UPLIZNA is safe or effective in children.Privacy...
Antibodies to myelin oligodendrocyte glycoprotein (MOG-IgG) have been described in patients with neuromyelitis optica spectrum disorders (NMOSD) without aquaporin-4 antibodies (AQP4-IgG). We aimed to identify the proportion of AQP4-IgG-negative NMOSD patients who are seropositive for MOG-IgG. In a...
Prognostic factors and disease course in aquaporin-4 antibody-positive patients with neuromyelitis optica spectrum disorder from the United Kingdom and Japan. Brain. 2012;135(6):1834-1849. doi:10.1093/brain/aws109 O’Connell K, Hamilton-Shield A, Woodhall M, et al. Prevalence and ...
To evaluate the prevalence of aquaporin-4 (AQP4) antibody in Thai patients with idiopathic inflammatory demyelinating CNS diseases (IIDCDs) and to analyze ... Siritho,Nakashima,Takahashi,... - 《Neurology》 被引量: 121发表: 2011年 加载更多研究...
The identification of NMO-IgG, a pathogenic antibody against aquaporin-4 (AQP4), delineated NMO from MS.Early, accurate diagnosis of NMO permits treatment with appropriate acute and long-term immunosuppressive agents that are critical to mitigate the risk of disability associated with this disease. ...
Key Wo rds :burn injury;cerebral edema;aquaporin一4:aq uapo rin-4 mRNA;arginine vas opress in; brain injury S hifang Luo "A- ,M ast er, L ec ture r,De pa rtm ent of A na tom y, C hongq ing Medica l U nive rs ity , C hongq ing ...
What is it called when cell energy is required for substances to pass across the plasma membrane? Explain how membrane flow participates with membranes that are part of the endomembrane system, but also part of the plasma membrane. What is an...
Moreover, IL-6 is also involved in producing anti-aquaporin-4 antibodies, and it has been reported that IL-6 has a higher level in NMOSD [72]. Intracerebral hemorrhages after vaccination due to central venous sinus thrombosis [68], vasculitis [61], and Moyamoya disease with Sjogren disease ...
Cerebral edema is reduced, in part, by regulating the expression of aquaporin 4 (a water channel) present in astrocytes [298]. PG has been tried in clinical trials due to its pluripotential role after multiple animal studies supported its use in TBI. Phase II clinical trials have shown ...
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