Trastuzumab is a humanized monoclonal antibody that binds to HER-2 with high specificity, preventing the recombination of EGF and HER-2, thereby slowing down cancer cell growth. Studies have also shown that Trastuzumab can reduce the expression of HER-2 on the surface of cancer cells. Additionall...
[21]. Yin H, Li L, Feng X, et al. 2D4, a humanized monoclonal antibody targeting CD132, is a promising treatment for systemic lupus erythematosus. Signal Transduct Target Ther. 2024;9(1):323. [22]. Wang L, Yin H, Jiang J, ...
Based on studies, infected persons to more severe SARS-CoV-2 disease have higher plasma IL-6 levels, and therefore it can be consid- ered as a negative prognostic biomarker for surviving [11]. However, tocilizumab, an anti-human IL-6 receptor, is a humanized monoclonal antibody which ...
A high correlation exists between HER2/neu protein over-expression and gene amplification (FIGURE 2). Trastuzumab is a humanized monoclonal antibody against HER2/neu. It was developed through research that demonstrated the importance of HER2/neu over-expression in b...
aGood tomorrow must reply to you 好明天必须回复您[translate] astaey staey[translate] aatrioventricular canal defect 房室的运河瑕疵[translate] aLebrikizumab (INN) is a humanized monoclonal antibody and an experimental immunosuppresive drug for the treatment of asthma that cannot be adequately controlle...
Bevacizumab is a humanized anti-VEGF monoclonal antibody that has shown relevant anti-tumor activity in a variety of solid neoplasms. A small randomized phase II trial suggested this drug was also active in GEP-NETs [107]. In this study, 44 patients on stable doses of somatostatin analogues ...
Ocrelizumab: A humanized anti-CD20 monoclonal antibody has also been evaluated in SLE (Chaichian et al 2013). Antibody against CD22: B cell depletion using CD22 as a target has been studied as a potential therapy in SLE. Epratuzumab is a humanized monoclonal antibody against CD22. SYSTEMIC ...
Aimovig is a fully humanized monoclonal antibody that works by binding to the calcitonin gene-related peptide receptor. Ajovy, Emgality, and Vyepti are humanized monoclonal antibodies that target the calcitonin gene-related peptide ligand.
aLebrikizumab (INN) is a humanized monoclonal antibody and an experimental immunosuppresive drug for the treatment of asthma that cannot be adequately controlled with inhalable glucocorticoids. The drug was created by Tanox under the name TNX-650, and a phase I clinical trial for refractory Hodgkin...
Trastuzumab is a humanized monoclonal antibody that selectively binds to the human EGFR (HER)-2 protein, indicated for the treatment of metastatic breast cancers with over expression of HER-2 protein. The incidence of trastuzumab-induced pneumonitis is 0.4 to 0.6%. Trastuzumab-induced pneumonitis may...