Drugs are classified into five distinct schedules that weigh medical benefits against their potential for abuse as called for by Congress in the Controlled Substances Act of 1970. Explore the drug classification process, and discover examples of Schedule I and Schedule...
How much do we know about drug handling by SLC and ABC drug transporters in children? Clin. Pharmacol. Ther. 94, 27–29 (2013). CAS PubMed Google Scholar Lopez-Lopez, E. et al. Polymorphisms in the methotrexate transport pathway: a new tool for MTX plasma level prediction in pediatric...
Lymphoma in patients with rheumatoid arthritis: what is the evidence of a link with methotrexate? Spontaneous remission may occur and a period of observation is advisable when clinically possible. If functional deterioration appears or there are signs of ... L Georgescu,SA Paget - 《Drug Safety》...
This is an overview of the current knowledge of adenosine receptor biology, from gene structure to expression, distribution, biochemical properties, pharmacological profiles, signalling and behavioural responses, focusing on receptor nomenclature and classification. CAS PubMed Google Scholar Fredholm, B. ...
Crohn’s disease is one of the major subtypes of idiopathic inflammatory bowel disease and is characterized by chronic transmural intestinal inflammation of the gastrointestinal tract anywhere from mouth to the anus, with a predilection for the small bowel. Cross-sectional imaging with computed tomograph...
drug treatment with steroidal anti-inflammatory agents (NSAIDs), corticosteroid injections, and biologics [blocker of tumor necrosis factor (TNF)] have all been shown to be effective, while conventional disease modifying drugs (DMARDs) such as sulfasalazine and methotrexate seem to work mainly for ...
[23]. Since then, more and more research has been conducted on its inhibition of different types of tumors and its mechanisms. In 2017, our research group first reported that Chlorogenic acid inhibits the growth of glioma by affecting the M1/M2 polarization classification of macrophages (i.e....
This week a Kenyan doctor has announced that two patients have been cured of HIV using Methotrexate, which is also in the same class (i.e. antimetabolites) as Azacytidine (mentioned by another user in this forum as the cure for an HTLV patient in Greece). Hopefully this means that drugs...
Although the new classification criteria for APS include the involvement of a microvascular domain [46], there is no mention of possible liver involvement. Further research is needed to elucidate if there is a sound association between aPL/APS and PSVD. Therefore, in cases of microvascular ...
Gold nanoparticles have attracted enormous scientific and technological interest due to their ease of synthesis, chemical stability, and unique optical properties. Proof-of-concept studies demonstrate their biomedical applications in chemical sensing, biological imaging, drug delivery, and cancer treatment. ...