Cortisol is the most important human glucocorticoid (a class of steroid hormones) produced in the cortex of the adrenal glands. In times of stressful situations, the adrenal glands secrete the“stress hormone”cortisol as part of your coping mechanism. This hormone is also released when your blood...
Interactions:MultiHance may prolong the exposure of the following drugs: cisplatin, doxorubicin, daunorubicin, vincristine, methotrexate, etoposide, tamoxifen and paclitaxel. Some patients may experience a rare, harmless disorder called Dubin-Johnson syndrome, which causes the liver to turn black. Risk of...
Gofen 400 is used to treat mild to moderate pain, reduce fever in some cases. However, the drug can cause some problems, so its use should be under the direction of a doctor.
which helps lessen inflammation. Not only do these drugs help manage pain, but they can reduce further joint damage, as they aim to stop the disease’s progression and rebalance the immune system. This class of drugs can be nonbiologic, like methotrexate, or biologic, like Humira or Remicade...
aSeveral syndromes of methotrexate pulmonary toxicity have been described.218 The most common is a hypersensitivity reaction, which presents subacutely with dyspnea (93%), dry cough (83%), and fever (69%), with diffuse interstitial infiltrates (Fig. 12).215 Clinical presentations vary and may ...
Biologics are medicines made from living cells. They belong to a class of drugs called disease-modifying antirheumatic drugs (DMARDs). They treat rheumatoid arthritis (RA) by targeting specific molecules involved in the inflammation process.
Both Nexium and Prilosec belong to the class of medicines called proton pump inhibitors (PPIs). Even though there are many similarities between them, there are several differences, such as: Nexium is a brand name for esomeprazole and Prilosec is a brand name for omeprazole ...
METTL16 is a class-I methyltransferase that is responsible for depositing a vertebrate-conserved S-adenosylmethionine site. Since 2017, there has been a growing body of research focused on METTL16, particularly in the field of structural studies. However, the role of METTL16 in cell biogenesis ...
Methotrexate(Trexall) Pentostatin(Nipent) Ruxolitinib(Jakafi). This is a recently approved drug for acute GVHD for ages 12 and over. It targets enzymes called JAKs (Janus-associated kinases) that play a role in developing cancer. Monoclonal antibodiesare biologic, or manmade, drugs that target ...
The first recommended treatment is similar for every patients including methotrexate frequently combined with low dose steroids. Anyway, EULAR recommends to guide second line treatment decisions based on the use of prognostic factors of outcome (eg, early erosion, high disease activity, rheumatoid ...