Over the past decade, cancer stem cells have emerged as the centerpiece of cancer research, having a major role in resistance to conventional therapy and in the metastatic spread of tumours. The authors discuss the biological complexity of this subpopula
Flow cytometry (FCM) analysis of the BM aspirate cells using the EuroFlow lymphoid screening tube (LST) and antibody panel for NK cell chronic lymphoproliferative diseases (NK-CLPD) [7], complemented with other cell surface markers, showed that the neoplastic cells were positive for CD45 (high...
The brain has been considered an immunologically privileged organ in part due to the presence of the blood–brain barrier (BBB), which prevents the entry of blood-born cells and other immune molecules from peripheral system into the central nervous system (CNS). However, multiple evidence indicate...