CD8 T cellT cell repertoireT cell receptorAgingThe memory response to LCMV in mice persists for months to years with only a small decrease in the number of epitope specific CD8 T cells. This long persistence is associated with resistance to lethal LCMV disease. In contrast to studies focused ...
GP(33-41), a 9-aa-long peptide, is the optimal sequence of the GP1 epitope of lymphocytic choriomeningitis virus, and can upregulate H-2Db molecules at the RMA-S (Db Kb) cell surface with a SC50 of 344 nM. GP(33-41) Epitope is a strong agonist of CD8 T cells from P14 TCR-tra...
Alternative choices Quantity Add to wishlistBulk Quote This is amino acids 25 to 33 fragment of human melanoma antigen gp100. This H-2Db restricted epitope is recognized by T cells. The gp100-specific, H-2Db-restricted, CD8+ T cells are capable of recognizing B16 melanoma but not normal ...
2007. Phenotypic and functional analysis of LCMV gp33-41-specific CD8 T cells elicited by multiple pep- tide immunization in mice revealed the up-regulation of PD-1 expression on antigen-specific CD8 T cells. Cell. Mol. Immunol. 4:431- 437.Yi Liu 1,2,4 ,Lihui Xu 3,4 ,Yiqun Jiang ...
2007. Phenotypic and functional analysis of LCMV gp33-41-specific CD8 T cells elicited by multiple pep- tide immunization in mice revealed the up-regulation of PD-1 expression on antigen-specific CD8 T cells. Cell. Mol. Immunol. 4:431- 437.Liu Y, Xu L, Jiang Y, Sun J, He X. 2007...
2007. Phenotypic and functional analysis of LCMV gp33-41-specific CD8 T cells elicited by multiple pep- tide immunization in mice revealed the up-regulation of PD-1 expression on antigen-specific CD8 T cells. Cell. Mol. Immunol. 4:431- 437.Yi Liu 1,2,4 ,Lihui Xu 3,4 ,Yiqun Jiang ...
No significant effect in the endogenous GP33–41 LCMV-specific response after the transfer of 2×103 P14 CD8 T cells.Georgia, FousteriAmy, DaveAmy, JuedesTherese, JunttiBret, MorinLisa, TogherDonna, L. FarberMatthias, von Herrath
Consistent with these findings, the adoptive transfer of spleen cells from immunized mice to naïve syngeneic mice was able to transfer anti-tumor effect, suggesting that GP10025–33 peptide-specific immune response was induced. Further studies showed that, CD8+ T cell proliferation and the ...