Ketamine is a potent NMDA antagonist among the family, and acts by inhibiting dorsal root ganglia. It is also known to have anti-inflammatory effects; theoreti- cally, it should be a good agent for NCP relief. Its analgesic effect is at subanesthetic doses. However, ...
nicotinic acetylcholine receptor NMDA: N-methyl D-aspartate WHIMS: Women's Health Initiative Memory Study.References Hardy J, Selkoe DJ: The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science. 2002, 297: 353-356. 10.1126/science.1072994. Artic...
Daclizumab is a humanized immunoglobulin G1 (IgG1) mAb that reversibly binds the so-called Tac epitope (binding site for IL-2) on the α-subunit (CD25) of the high-affinity IL-2 receptor (IL-2R-HA), which is highly expressed on activated T lymphocytes and regulatory T (Tregs) cells ...
Through the detection of SARS-CoV-2 RNA in the cerebrospinal fluid (CSF), meningitis/encephalitis was reported to be associated with SARS-CoV-2 accompanied by seizures [20]. A patient affected by COVID-19 was reported with his primary presentation as focal status epilepticus [21,22]. Most ...
Medically relevant alphaviruses include Venezuelan, Western, and Eastern Equine Encephalitis viruses (VEEV, WEEV, and EEEV), Ross River virus (RRV), and Chikungunya virus (CHIKV). In humans, alphaviruses can cause acute infections marked by high viremia and symptoms, including fever, rash, ...