Dipeptidyl peptidase-4 (DPP4) inhibitors (see discussion below) are weak anti-hyperglycemic agents, are not first line glucose lowering drugs, and probably should be stopped in anyone with any indications of volume depletion or reduced kidney function. Non-hospitalized patients with T1DM as well as...
“I'm particularly excited this year about the novel oral therapies that are coming out for treating sleep apnea as there's been some promising work over the last couple of years. But a lot of the time patients will tell us they can't tolerate continuous positive airway pressure or they c...
There are no more “mess halls”, now there are Dining Facilities (DFAC). These are large, consolidated facilities, with the latest equipment and technology, and offer a wide variety in their menus, because soldiers are no longer bound to eat in “their” DFAC, they can eat in any DFA...
https://www.fda.gov/emergency-preparedness-and-response/mcm-legal-regulatory-and-policy-framework/emergency-use-authorization#coviddrugs, retrieved February 11, 2023. Kelley, B. Developing therapeutic mAbs at pandemic pace. Nat Biotechnol 38, 540–545 (2020).https://do...
What are the effects of drugs on Treg cells in multiple myeloma, and what are the applications of treg cells in therapy? Introduction Multiple myeloma (MM) is the most common form of plasma cell malignancy, accounting for about 1.7% of all malignant tumors [1]. Although the use of a vari...
There are currently several antivirals that may be used to treat people with COVID-19, including those infected with the XBB.1.5 variant. Some of the most commonly used antiviral drugs for COVID-19 include: Remdesivir: This antiviral drug targets the RNA polymerase enzyme of the virus, which...
Adoptive cell therapy is a form of personalized medicine that expands or modifies immune cells from a patient or donorex vivoso that the immune cells are able to recognize and kill tumor cells.The modified cells are then reinfused into the patient. Often referred to as “living drugs,” exam...
Certain drugs prescribed for metabolic conditions, like stimulants or weight-loss medications, can negatively affect sleep. For example, some medications that support metabolism may trigger insomnia or poor sleep quality. Additionally, short sleep duration (less than 6 hours) among sleeping pill users...
Acute phase proteins in schizophrenia, mania and major depression: modulation by psychotropic drugs. Psychiatry Res. 1997;66:1–11. CAS PubMed Google Scholar Cazzullo CL, Saresella M, Roda K, Calvo MG, Bertrando P, Doria S, et al. Increased levels of CD8+ and CD4+ 45RA+ lymphocytes ...
Importantly, senolytic drugs have the potential to be used as an effective treatment for DEARE even after DEARE becomes a progressive disease [212], but it is not yet clear how this might be used in and for elderly exposed individuals. As mice age, like humans, health issues and ...