The intensification of agriculture has led to the widespread use of chemical pesticides for the control of pests and diseases. However, it has been demonstrated that these pesticides can enter the animal body through a number of different pathways, with
There is an acknowledged need for public sector involvement in the development of new antimicrobials, to overcome market failure and provide drugs that are socially necessary, but which are insufficiently supplied by current market-driven arrangements. This ‘public goods’ nature of antimicrobials is ...
meaning there are still several patients with difficult epilepsy to treat that need effective therapies. This is the case, especially for patients who live withautoimmune epilepsy, which presents specific clinical manifestations. According to a review published in theJournal...
At The STI Project, we use the term STI and STD interchangeably, and we’ve chosen to continue using STD in many places because people are more familiar with it, so it’s more accessible to the general public. Some posts and pages will also contain a lot of the term STI because we a...
the Kefauver–Harris Amendment of 1962 required that medications needed to demonstrate empirical evidence for their safety and efficacy in terms of treating a specific disease in order to be sold. Then in the 1970s, the FDA mandated that efficacy testing of new drugs required controlled clinical ...
In the United States, the Food and Drug Administration (FDA) does not regulate supplements the way it regulates prescription drugs. That means some supplement products may not contain what the label says. Whenchoosing a supplement, look for third-party tested products and consult a healthcare pro...
Animal study Before starting clinical trials, the safety and effectiveness of new drugs are usually tested in animal models [28], so animal study is considered as preclinical research, pos- sessing important significance [29, 30]. Likewise, the methodological quality of animal study also needs ...
An update on COVID-19: SARS-CoV-2 variants, antiviral drugs, and vaccines 2023, Heliyon Citation Excerpt : In the meantime, Johnson & Johnson, Moderna, and Pfizer reported that their vaccines are still effective against SARS-CoV-2 [118]. Moreover, Moderna reported that they are checking th...
Before starting clinical trials, the safety and effectiveness of new drugs are usually tested in animal models [28], so animal study is considered as preclinical research, possessing important significance [29, 30]. Likewise, the methodological quality of animal study also needs to be assessed [30...
Patients taking drugs with potential interference with clotting, such as warfarin, clopidogrel, and those who required transfusion of blood products such as fresh frozen plasma and packed red blood cells were excluded from the study. This study was a controlled, randomized, non-blinded trial. Due ...