Some experts in this setting recommend the use of haloperidol, cited in WHO 2008 list of necessary drugs in paediatric palliative care, to reduce midazolam [134, 144]. Single-centre experience reported as effective the use of propofol particularly in adolescents or if the first-line strategy was...
Elevation of IL-18 supports a major inflammatory renal insult. This provides evidence to support investigation of anti-inflammatory drugs for cisplatin nephrotoxicity prevention. Disclosure: Funded by British Heart Foundation Corresponding author: Alan Cameron 34. Information giving in breast cancer: A ser...
To determine taxa-specific patterns in reservoir colonization, we performed WGS of Enterobacterales,Pseudomonas, andStenotrophomonasisolates from environmental, fecal, and blood samples from both ICUs. AR Enterobacterales are some of the most feared AROs for HAIs8and many are associated with human fecal...
Study of mechanisms by which antibodies recognize different viral strains is necessary for the development of new drugs and vaccines to treat COVID-19 and other infections. Here, we report 2.5 Å cryo-EM structure of the SARS-CoV-2 Delta trimeric S-protein in complex with Fab of the rec...
protein complex formation or dissolution. This library is the first output of our modular approach and could be used as a standalone resource to help design mutations or drugs to interfere with PPIs, for functional characterization of protein complexes or as training or evaluation data for ...
Tumor progression locus 2 (Tpl2) is a member of the mitogen-activated protein kinase kinase kinase (MAP3K) family of serine/threonine kinases. Deletion of the Tpl2 gene is associated with a significantly higher number of papillomas and cutaneous squamous