E. et al. Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice. Nature 406, 641–645 (2000).Using telomerase-deficient mice, the authors provide in vivo evidence that telomere erosion in a p53-null background promotes the development of epithelial tumours that ...
1. 1 Experimental animals: Experimental animals: Male ICR mice (SPF grade, weight 20±2g) were purchased from the Institute of Experimental Animals, Chinese Academy of Medical Sciences, China Union Medical College, Beijing Huafukang Biotechnology Co., Ltd., certificate number: SCXK (Beijing) 2009...
Because there are very few experimental data, it must be considered that these may be caused by artifacts. The experimental evidence regarding cancer concerns only genetically modified mice, artificially susceptible to cancer. It can be considered that these results cannot be reliably extrapolated to ...
fracticranius not only engaged in polypoly mating, but they also had some sexual dimorphism and large testes. The evidence that supports the sexual dimorphism claim can be seen when the body size of the female and male are compared since the male’s body size is 41 kg larger than the ...
E. et al. Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice. Nature 406, 641–645 (2000).Using telomerase-deficient mice, the authors provide in vivo evidence that telomere erosion in a p53-null background promotes the development of epithelial tumours that ...
转基因或基因敲除小鼠行为学表型鉴定手册 What's Wrong With My Mouse?--Behavioral Phenotyping of Transgenic and Knockout Mice (Second Edition) 热度: using liquid crystal spatial light modulators for closed loop tracking and beam steering with phase holograpy ...
In another acute model of AD, male ICR mice were subjected to intrahippocampal injections of okadaic acid (a phosphatase inhibitor). Subsequently, groups of 20 mice were treated intravenously with free curcumin or nanoparticles for 10 days (solubilisation not described; data for behaviour of N = ...
9 RegisterLog in Sign up with one click: Facebook Twitter Google Share on Facebook DDY AcronymDefinition DDYDecatur-Dekalb YMCA(Young Men's Christian Association; Decatur, GA) DDYDefining Diabetes in Youth(Wake Forest University) DDYDevlet Demir Yollarý(Turkey) ...
in intravenously injected ICR (CD-1) mice [66]. This drug has anti-nociceptive effects and cannot naturally cross the BBB. Nevertheless, using the tail-flick test, which consists of a pain response test, it was possible to confirm the brain delivery capacity of this nanocarrier system [66]...
At 300 µg/kg PCB 126 elicited a subset of weaker effects compared with 30 µg/kg TCDD in immature, ovariectomized C57BL/6 mice. % time spent in the center, social interaction time, and the number of rearing were significantly reduced in PCB treated group None of the treatments (...