BAZ2-ICR (Compound 13) shows very high solubility (25 mM in D2O), a measured log D of 1.05, high stability in mouse microsomes, and permeation in the CaCo-2 model and thus a suitable profile for oral and intravenous gavage. BAZ2-ICR (5 mg/kg) shows 70% bioavailability and moderate ...
nutrients Article Protective Effect of Gallotannin-Enriched Extract Isolated from Galla Rhois against CCl4-Induced Hepatotoxicity in ICR Mice Jun Go 1, Ji Eun Kim 1, Eun Kyoung Koh 1, Sung Hwa Song 1, Ji Eun Sung 1, Hyun Ah Lee 1, Young Hee Lee 2, Yong Lim 3, Jin Tae Hong 4 and ...
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