ICR scid mice are an immunodeficient strain comparable to the C.B-17 scid, but with reduced incidence of Ig production. Developed by Fox Chase Cancer Center.
Here we describe the occurrence of poliomyelitis in ICR-SCID mice resulting from injection of LDV-contaminated basement membrane matrix. After exposure to LDV, a subset of mice presented with clinical signs including paresis, which was associated with atrophy of the hindlimb musculature, and ...