Weight-based heparin dosing: clinical response and resource utilization. Clin Ther - CL, AB, et al. - 1998Lackie CL, Luzier AB, Donovan JA, Feras HI, Forrest A. Weight-based heparin dosing: clinical response and resource utilization. Clin Ther 1998;20:699-710....
Unfractionated heparin infusion therapy is often administered using a weight- based dosing strategy for the treatment of venous thromboembolism. In the last several decades, the prevalence of obesity in the United States has increased significantly.Is...
Heparin therapy improves clinical outcomes in patients with thromboembolic disorders [1-4], but the determination of appropriate heparin dosing is often problematic. Physicians' dosing decisions vary widely, as do their therapeutic goals [5]. Practice audits reveal frequent underdosing, with delays in...
The weight-based heparin dosing nomogram compared with a "standard care" nomogram. Ann Intern Med. 1993;119874- 881Google ScholarCrossref 30. Hull RDRaskob GERosenbloom D et al. Optimal therapeutic level of heparin therapy in patients with venous thrombosis. Arch Intern Med. 1992;1521589- ...
Evaluation of A Simplified Weight-Based Heparin Dosing Protocol in Patients With Unstable Ischemic SyndromesHoney, Tami N.; Laine, Greg A.; Puckett, William H.Abstract An abstract is unavailable. This article is available as HTML full text only....
Therefore, low-molecular weight heparin and warfarin remain the standard of care in this population. Objective: To assess weight-based enoxaparin dosing in VTE, with no capping of prescribed doses, comparing patients weighing >100kg with those weighing <100kg. The primary outcome was anti-Xa ...
Intravenous and subcutaneous weight-based dosing of the low molecular weight heparin tinzaparin (Innohep) in end-stage renal disease patients undergoing ch... Intravenous and subcutaneous weight-based dosing of the low molecular weight heparin tinzaparin (Innohep) in end-stage renal dis- ease patients...
Superior bioavailability and simple weight-based dosing have made low-molecular-weight heparins (LMWH) the preferred agents for treatment and prevention of venous thromboembolism (VTE) for most indications. Despite improved pharmacokinetics, there remain populations where appropriate LMWH dose intensity and...
In the dosing regimen, patients with the kg-based dosing regimen showed 2.6 times better response than those with the fixed dosing regimen. However, no difference in bleeding complications was observed. Conclusion: In the dosing regimen, the kg-based regimen that was the same as the venous ...
Heparin and Low-Molecular- Weight Heparin Mechanisms of Action, Pharmacokinetics, Dosing, Monitoring, Efficacy, and Safety Jack Hirsh, MD, FCCP, Chair; Theodore E. Warkentin, MD; Stephen G. Shaughnessy, PhD; Sonia S. Anand, MD; Jonathan L. Halperin, MD; Robert Raschke, MD, MS; Christopher...