The article discusses research being done on recommended lepirudin dosage for patients with heparin-induced thrombocytopenia (HIT). It references a study by B. Tardy et al published in the September 1, 2006 issue of the periodical "Blood." It cites that mean lepirudin dose is an independent ...
Dosing lepirudin in patients with heparin-induced thrombocytopenia and normal or impaired renal function: a single-center experience with 68 patients. The recommended dose (bolus 0.4 mg/kg followed by 0.15 mg/kg per hour) of lepirudin, a direct thrombin inhibitor licensed for treatment of heparin-...
This created a weakness in our original scheme, especially now that improved catheter-directed techniques and high-dose protocols can achieve improved perfusion in one third to one half of the time formerly required for lytic therapy. Therefore, we have subdivided category II into two levels, with...
Pharmacokinetics and pharmacodynamics of a therapeutic dose of unfractionated heparin (200 U/kg) administered subcutaneously or intravenously to healthy dogs Background: Heparin treatment has been recommended for dogs in hypercoagulable states such as disseminated intravascular coagulation, however, potential ...
Mean lepirudin dose appears to be an independent predictive factor for major haemorrhage in patients with heparin-induced thrombocytopenia (HIT), and the current dosing recommendations* in such patients appear to be too high, according to researchers from France. To identify predictive factors for ...
Prophylaxis of catheter-related deep vein thrombosis in cancer patients with low-dose warfarin, low molecular weight heparin, or control: a randomized, con... Whether an anticoagulant prophylaxis is needed for patients with cancer with a central venous catheter is a highly controversial subject. We...
Although the American College of Chest Physicians (ACCP) recommend that HF patients admitted to hospital should receive VTE prophylaxis with low-molecular-weight heparin (LMWH) or low-dose unfractionated heparin (UFH), recent reports suggest that medical patients at risk of VTE often receive sub-...
The benefit from pharmacological prophylaxis for venous thromboembolism (VTE) is uncertain probably due to doubts about the optimal agent and dose. We evaluated the benefit/risk ratio of different anticoagulant regimens in the prevention of VTE in patients with AIS. METHODS: The MEDLINE, EMBASE, ...
Low molecular weight heparin was administrated 6 hours after surgery until 11th day at the dose of 0.4 ml of Calcic Nadroparin 3800 UI s.c. daily for each patient.We evaluated the incidence of venous thromboembolism considering both pulmonary embolism and deep venous thrombotic events. Clinical ...
HDL cholesterol (HDL-C) was measured after precipitation with heparin and manganese (II) chloride (polyanion precipitation). LDL-C was calculated by subtracting HDL-C from the total cholesterol in the infranatant of the ultracentrifugation. Non-HDL-C was calculated by subtracting HDL-C from TC...