VP16-CREB fusion geneThe present application describes a cell that has integrated into its genome fusion molecule V16-CREB.Sung Ho Hahm
Expression of VP16-CREB, a constitutively active form of CREB, in hippocampal neurons of the CA1 region lowers the threshold for eliciting the late, persistent phase of long-term potentiation (L-LTP) in the Schaffer collateral pathway. This VP16-CREB-mediated L-LTP differs from the conventiona...
VP16-CREB fusion geneThe present application describes a cell that has integrated into its genome fusion molecule V16-CREB.Hahm, Sung Ho
VP16-CREB FUSION GENEThe present invention relates to a vp-creb fusion gene stably and efficiently expressing a transgene in a cell, and to a use of the same.HAHM, SUNG HO
Expression of VP16-CREB, a constitutively active form of CREB, in hippocampal neurons of the CA1 region lowers the threshold for eliciting the late, persistent phase of long-term potentiation (L-LTP) in the Schaffer collateral pathway. This VP16-CREB-mediated L-LTP differs from the ...
Furthermore, increased expression of cAMP responsive genes was compromised in cells resisting VP16CREB-mediated differentiation. CONCLUSION: A constitutively active CREB induces terminal differentiation in a subset of NBP2 cell population. Altered expression of cAMP responsive genes may account for ...
Gene expression profiling of facilitated L-LTP in VP16-CREB mice reveals that BDNF is critical for the maintenance of LTP and its synaptic capture. Neuron 2005; 48: 123-37.Barco A, Patterson S, Alarcon JM, Gromova P, Mata-Roig M, Morozov A et al (2005). Gene expression profiling of...