High-dose chemotherapy followed by autologous hematopoietic cell transplantation (AHCT) is an effective salvage therapy for patients with relapsed chemosensitive non-Hodgkin's lymphoma (NHL). However, the optimal conditioning regimen is unclear. Different conditioning regimens prior to AHCT have been ...
Recent studies indicate that p53-dependent apoptosis induced in normal tissues during chemo- and radiotherapy can cause severe side effects of anti-cancer treatments that limit their efficiency. The aim of the present work was to further characterise the role of p53 in maintaining genomic stability ...
Aggressive conventional chemotherapy compared with high-dose chemotherapy with autologous haemopoietic stem-cell transplantation for relapsed chemosensitive Hodgkin's disease: a randomised trial Lancet, 359 (2002), pp. 2065-2071 View PDFView articleView in ScopusGoogle Scholar 5 A. Colpo, E. Hochberg,...
chemoimmunotherapy for small cell undifferentiated carcinoma of the lung. Cancer 46:2543–2549 Google Scholar Aisner J, Ostrow S, Govindan S, Wiernik PH (1981) Leptomeningeal carcinomatosis. In: Small cell carcinomatosis of the lung. Med Ped Oncol 9:47–59 Aisner J, Whitacre MY, VanEcho ...
Recent studies indicate that p53-dependent apoptosis induced in normal tissues during chemo- and radiotherapy can cause severe side effects of anti-cancer treatments that limit their efficiency.The aim of the present work was to further characterise the role of p53 in maintaining genomic stability ...
VP 16-213 and cyclophosphamide in advanced breast cancer, a phase II study. Cancer Chemotherapy and Pharmacology 10: 154–157, 1983bEstapeA J, Cirera L, MillaA A, Doncel F (1983) VP 16-213 and cyclophosphamide in advanced breast cancer. Cancer Chemo- ther Pharmacol 10: 154...
ChemopurgingMP/VP16Progenitor recoveryMarrow graftingThe ability to eliminate malignant cells from bone marro (BM>while retaining sufficient numbers of normal progenitors to ensure. Engraftment, may well establish the future of autologous BM transplantation (ABMT) for hematologic malignancies. In this ...
(Abstract.)Crino L, Palladino MA, Darwish S et al. Combination chemo- therapy with cisplatin and teniposide(VM26) or etoposide (VP16) for brain metastasis of small-cell lung cancer (SCLC): A phase II study. Lung Cancer 1997; 18 (Suppl 1): 47 (Abstr)....
When used as a therapeutic modality for patients with acute leukemia in remission, supralethal chemo-radiotherapy and an allogeneic or syngeneic bone marrow (BM) transplant appears to be superior to conventional therapy(1). Selected patients with an acute non-lymphocytic leukemia in first remission,...