This tutorial deals with basic concepts of volume of distribution, the second most important parameter in pharmacokinetics but often challenging for students in clinical pharmacology. Its relationships with dose, concentration and amount in the body are discussed using a physical model and examples of ...
(2004) Volumes of distribution. Journal of Veterinary Pharmacology and Therapeutics, 27, 441-453.Toutain PL and Bousquet-Melou A (2004). Volumes of distribution. J. Vet. Pharmacol. Therap., 27: 441-453.Toutain PL, Bousquet - Melou A. Volumes of distribution. J Vet Pharmacol Therap, 2004;...
apparent volume of distribution Pharmacology The ratio of the total amount of drug in the body to the concentration of the drug in the plasma, or the 'apparent' volume necessary to contain the entire amount of a drug, if the drug in the entire body were in the same concentration as in ...
Volume of Distribution This is a preview of subscription content, log in via an institution to check access. Editor information Editors and Affiliations Section Behavioural Pharmacology, Institute of Psychiatry, King's College London, London, UK Ian P. Stolerman ...
- 《European Journal of Clinical Pharmacology》 被引量: 1092发表: 1985年 Urea space and total body water measurements by stable isotopes in patients with acute renal failure BACKGROUND: Knowledge of urea volume of distribution (Vurea) in patients with acute renal failure (ARF) is critical in ...
SSND Graaf,JAD Vries,WG Zijlstra - 《Cancer Chemotherapy & Pharmacology》 被引量: 5发表: 1986年 The volume of distribution of mannitol as a measure of the volume of extracellular fluid, with a study of the mannitol method THE VOLUME OF DISTRIBUTION OF MANNITOL AS A MEASURE OF THE VOLUME ...
Volume of Fluid (VOF) Method for the Dynamics of Free :流体体积(VOF)的释放动力学的方法 热度: 相关推荐 THE APPARENT VOLUME OFDISTRIBUTION OF POTASSIUM INJECTED INTRAVENOUSLY* BYALEXANDER W.WINKLERt ANDPAUL K.SMITHS: (From the Departments ofInternal Medicine and ofPharmacology and Toxicology, Ya...
PharmacologyThe use of in silico approaches for successful prediction of pharmacokinetic properties of compounds during new drug discovery has been increasing exponentially. These in silico models, for the prognosis of absorption, distribution, metabolism and excretion (ADME), are invariably based on the...
We conclude that blood translocation from the abdominal region may participate in the development of DOCA salt hypertension.doi:10.1096/fasebj.23.1_supplement.1017.7Bridget Mahon SeitzPharmacology and ToxicologyMichigan State UniversityEast LansingMIGregory Fink...
Methods Fifteen haemodynamically unstable infants with volume overload admitted to a paediatric intensive care unit were treated with an aggressive furosemide ... MMJVD Vorst,KV Holthe,JD Hartigh,... - 《British Journal of Clinical Pharmacology》 被引量: 19发表: 2010年 加载更多0关于...