References in periodicals archive ?The volume of distribution, also known as the "apparent volume of distribution," quantifies how the drug disperses throughout the body. A primer on pharmacokinetics This value was normalized (N.CLT) by dividing App.CLT by the weight of the bird; the ...
Journal of Pharmaceutical SciencesM. Gibaldi and D. Perrier. Drug elimination and apparent volume of distribution in multicompartment systems. J. Pharm. Sci. 61 :952–954 (1972).Gibaldi J., Perrier D. (1972) Drug elimination and apparent volumen in multicompartment systems. J. of ...
摘要: The model-independent estimation of physiological steady-state volume of distribution ($$V_{dss,p}$$Vdss,p), often referred to non-compartmental analysis (NCA), is historically based on the linear com关键词: Steady-state volume of distribution Simultaneous first-order and Michaelis–Menten...
内容提示: International Journal of Pharmaceutics 319 (2006) 82–97QSPR models for the prediction of apparent volume of distributionTaravat Ghafouriana,b,∗, Mohammad Barzegar-Jalalia, Siavoush Dastmalchic,Tina Khavari-Khorasania, Nasim Hakimihaa, Ali NokhodchibaDrug Design and Chemometrics ...
qsprvolumepredictiondistributionmodelsapparent InternationalJournalofPharmaceutics319(2006)82–97QSPRmodelsforthepredictionofapparentvolumeofdistributionTaravatGhafouriana,b,∗,MohammadBarzegar-Jalalia,SiavoushDastmalchic,TinaKhavari-Khorasania,NasimHakimihaa,AliNokhodchibaDrugDesignandChemometricsLaboratory,DrugAppliedRe...
Furthermore, we assessed the effect of LSV, which is correlated with MR estimates, on the longitudinal increase in the levodopa-equivalent dose (LED) during the 4-year follow-up period using a linear mixed model. After controlling for intracranial volume, there was a significant positive ...
Production and beneficial impact of biochar for environmental application: A comprehensive review YuwenZhou, ...Mukesh KumarAwasthi, inBioresource Technology, 2021 2.1.3Pore size and pore volume distribution Although biochar has a large surface area, its ability to utilize water and adsorb gases is ...
The difficulties in establishing such relationships in part may be due to design limitations of previous studies. Difficulties arise in choosing optimal patient and control samples, in eliminating the possible confounding effects of substance abuse and antipsychotic medication, and in measurement of brain...
The volume of distribution of a drug (V d ) is a useful pharmacokinetic parameter for relating drug concentration in the plasma to the total amount of drug in the body. Disease-induced changes in V d may well result in a change in the therapeutic or toxic significance of a given plasma ...
While the growth curve of brain gray matter volume (GMV) peaks in preadolescence, brain maturational processes, including synaptic pruning and axon myelination, will continue throughout the entire period of adolescence17. Furthermore, these brain maturational processes are associated with brain re-...