Viruses are the most abundant biological entities on Earth and play a significant role in the evolution of many organisms and ecosystems. In pathogenic protozoa, the presence of viruses has been linked to an increased risk of treatment failure and severe clinical outcome. Here, we studied the mol...
The historical significance of the poxviruses is profound, largely due to the enduring impact left by smallpox virus across many centuries. The elimination of smallpox is a remarkable accomplishment in the history of science and medicine, with centuries of devoted efforts resulting in the ...
In contrast, within BRVs, the probability of recombination increases. The data reported here provide genetic information to assist in the identification of diagnostic signatures and research tools for BRAV. 展开 关键词: BRAV RS3X sequence phylogeny evolution bioinformatics ...
Host immunity has a dual role in governing the pace of virus evolution: innate immunity acts as a constraint on the generation of new virus variants, whereas adaptive immunity selects for immune escape mutants The acute nature of influenza virus infections and population-level epidemics provides lim...
The difference between invertebrates and vertebrates most likely reflects differences in species numbers, population size, abundance, and the evolution of adaptive immunity in the latter. That RNA viruses may co-diverge with their mammalian hosts has been known for several decades, and is well ...
Conclusion: The evolutionary analysis based on the historical data and utilizing the Bayesian relaxed clock allowed us to determine the molecular evolution rates of the AT-rich genomes of the vertebrate poxviruses and assess the times of their emergences. Involvement of a large set of the conserved...
Discovery: Historical records on the scourges caused by viruses have been found in ancient relics. The virus was first described as a filterable transmissible agent that causes disease in plants and animals. • Definition: A virus is a “submicroscopic and intracellular parasite.” Viruses are fo...
[Advances in Virus Research] Environmental Virology and Virus Ecology Volume 101 || Ecological Complexity in Plant Virus Host Range Evolution MJ Mcleish 被引量: 0发表: 2018年 Evolutionary Determinants of Host and Vector Manipulation by Plant Viruses Plant viruses possess adaptations for facilitating ...
in our understanding of host-virus interactions in dense, substrate-bound and heterogeneous biofilms3. In particular, major questions exist with regard to host range, viral life cycle, modes of dispersal and host-virus co-evolution in complex microbial communities where genetically diverse and ...
This study characterized the vaccinia-virus soluble type I IFN receptor encoded by the B18R gene, which has broad species specificity and might have aided vaccinia-virus replication in many host species during evolution. Article CAS PubMed Google Scholar Verardi, P. H., Jones, L. A., Aziz...