non-canonical autophagySopFV-ATPaseConjugation of the Atg8 (autophagy related 8) family of ubiquitin-like proteins to phospholipids of the phagophore is a hallmark of macroautophagy/autophagy. Consequently, Atg8 family members, especially LC3B, are commonly used as a marker of autophagosomes. ...
v-atpase-d2 英文回答: The molecular weight of v-ATPase-d2 is approximately 70 kDa. This protein is a subunit of the vacuolar ATPase (v-ATPase) complex, which is responsible for acidifying intracellular compartments such as lysosomes and endosomes. The v-ATPase complex is composed of multiple...
Mechanisms of regulating H+-ATPase activity: • Recycling of H+-ATPase-containing vesicles to and from the plasma membrane; • Glucose-sensitive assembly/disassembly of the holoenzyme complex. Molecular pathology H+-ATPase mutations in the A3 gene cause recessive osteopetrosis; they have been impl...
V-ATPase, subunit B is a non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. Alternative names: Vacuolar proton pump subunit B1, vacuolar H+-ATPase subunit B, V-ATPase 57 kDa subunit. 应用类型 Western blot (WB)
The E and G subunits of the yeast V-ATPase interact tightly and are both present at more than one copy per V1 complex. The Journal of Biological Chemistry, 2006, 281(32): 22752-22760. [11] Powell B, Graham L A, Stevens T H. Molecular characterization of the yeast vacuolar H+-...
V-ATPase is an enzyme responsible for acidification of intracellular compartments. Subunit D is the peripheral subunit of V1 complex. Alternative name: Vacuolar proton pump subunit D, vacuolar H(+)-ATPase subunit D 应用类型 ELISA (ELISA), Western blot (WB) ...
stalkdomain,whichmakesthemacomplexwithintegratedstructureandfunction.Thevacuolar30 ATPaseisinvolvedinavarietyofvitalintra-andinter-cellularprocessessuchasactivetransport ofmetabolites,cellhomeostasisandneurotransmitterrelease.Herewesummarizesthestructure, functionandregulationmechanismsofV-ATPases. ...
The V-ATPase proton pump is an enzymatic macro-complex composed of eight V1, six V0 and two accessory subunits (Supplementary Fig. 1a). V-ATPase structure and composition are well conserved throughout evolution6,12,13. In Drosophila, there are 13 and 18 partially redundant orthologues for th...
The distribution of V-ATPase was more restricted since there were SNX10 vesicles that were negative for V-ATPase. We next tested whether V-ATPase directly interacted with SNX10. We screened various subunits of the V-ATPase complex and found that the V1D subunit co-immunoprecipitated with SNX10...
V_ATPase分子结构与功能及其RNAi技术在害虫防治中的应用研究进展