In the present report, we have examined the effects of expression of the c-fms, v-abl, or v-myc oncogene in a clonal hematopoietic progenitor cell line 32D cl 3. The 32D cell line is nonmalignant in vivo and is dependent upon a source of Interleukin-3 (IL-3) for growth in vitro...
研究目的 旨在评估InO/地塞米松(DEX)诱导治疗CD22+、BCR::ABL- ALL老年患者的疗效。 研究方法 在43例可评估的CD22+、BCR::ABL- ALL老年患者中,患者接受了最多3个周期的InO/地塞米松治疗,以及最多6个周期的适应年龄的GMALL研究方案的...
Cellular signaling events elicited by v-abl associated with growth factor independence in an interleukin-3-dependent cell line. P, Evans CA, Whetton AD: Cellular signaling events elicited by v-abl associated with growth factor independence in an interleukin-3-dependent cell line. ... PJ Owen,P...
《A modified DAW-22 compound F-B1 inhibits Bcr/Abl and induces apoptosis in chronic myelogenous leukemia cells》 作者:Wang Fengling; Wang Jinhui; Chong Zhaozhong; Mu Yanling 期刊:Anti-Cancer Drugs 影响因子:2.535 PMID:30422832 《Probiotic Bacillus subtilis CW14 reduces disruption of the epithelial...
BCR-ABL1 [E255V]/BaF3 Host Cell: Ba/F3 Stability: 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) Application: Anti-proliferation assay and PD assay Freeze Medium: 90% FBS+10% DMSO Complete Culture Medium: RPMI-1640...
Cell Line Name: BCR-ABL1 [M244V]/BaF3 Host Cell: Ba/F3 Stability:16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) Application: Anti-proliferation assay and PD assay Freeze Medium: ...
in BCR::ABL1 transcripts after initiation of first-line TKI therapy has also been shown to be an independent predictor of TFR eligibility and sustained TFR.238 Resumption of TKI therapy immediately after recurrence results in the achievement of DMR in almost all patients. In the STIM study, mol...
基于此,为了更好的观察和研究轻链的主要重排现象(初级重排),研究人员利用基因编辑CRISP/Cas9的技术特异性敲除了v-Abl细胞 中5个Jks基因中的4个(Jk1~Jk4)以及下游的k敲除元件(kappa deleting element),而仅仅保留了一个Jk5,尽可能的保证Jk...
The parental cell line, the 32D/v-Abl–transformed cell line,23, 28 and the 32D/src–transformed cell line24 were transfected, by electroporation, either with the pRC/CMV expression vector alone or carrying the wild-type human β4 integrin subunit cDNA.5 The 32D/v-Abl cells were also ...
Cell Line Name: BCR-ABL1 [E255V/T315I]/BaF3 Host Cell: BA/F3 Stability:16 passages(in-house test, that not means the cell line will be instable beyond the passages we tested.) Application: Anti-proliferation assay and PD assay