IrinotecanSpringer Berlin HeidelbergClarke D, Burchell B. 1994. The uridine diphosphate glucuronosyltransferase :
3-glucuronosyltransferases, responsible for the completion of the protein-glycosaminoglycan linkage region of proteoglycans and of the HNK1 epitope of glycoproteins and glycolipids. In humans the enzyme galactose-beta-1, 3-glucuronosyltransferase I completes the synthesis of the common linker region ...
UGT1A1The role that the phase-II reaction, glucuronidation, plays in the biotransformation of endo and xenobiotics is discussed with particular emphasis given to the UGT1A1 isoenzyme. This individual isoenzyme is responsible for both the mono and di-glucuronidation of bilirubin together with the ...
Uridine diphosphate glucuronosyltransferase 1A1 prevents the progression of liver injury Jin-Lian Jiang, Yi-Yang Zhou, Wei-Wei Zhong, Lin-Yan Luo, Si-Ying Liu, Xiao-Yu Xie, Mao-Yuan Mu, Zhi-Gang Jiang, Yuan Xue, Jian Zhang, Yi-Huai He ...
Recognition of uridine diphosphate glucuronosyl transferases by LKM-3 antibodies in chronic hepatitis D. Lancet 1994;344:578-81.Philipp T,Durazzo M,Twei T,et al.Recognition of uridine diphosphate glucuronosyl transferases by LKM3 antibodies in chronic hepatitis. Hepatology . 1990...
The uridine diphosphate glucuronosyl transferase 1A1 (UGT1A1) is an important member of the UGT1A family. It facilitates the metabolism and subsequent excretion of potentially toxic xenobiotics, carcinogens, estrogens, bilirubin and therapeutic drugs. The UGT1A1 gene spans about 160 kb and is loca...
30March2016 glucuronidation activities Yan-Qing Liu*, Ling-Min Yuan*, Zhang-Zhao Gao,Yong-Sheng Xiao, Hong-Ying Sun, Lu-Shan Yu & Su Zeng Uridine diphosphate glucuronosyltransferase 1A (UGT1A) is a major phase II drug-metabolism enzyme superfamily involved in the ...
2) Uridine Diphosphate Glucuronosyltransferase 1A1(UGT 1A1) 尿核苷二磷酸葡萄糖苷酰转移酶1A13) Urine NAG/UCr 尿N-乙酰-β-D-氨基葡萄糖苷酶/尿肌酐4) UDP-acetylglucosamine pyrophosphorylase 尿苷二磷酸乙酰葡糖胺焦磷酸化酰5) N-acetylglucosamine-1-phosphate uridyltransferase N-乙酰葡萄糖胺-1-...
尿苷二磷酸葡萄糖醛酸转移酶(UDP-glucuronosyltransferases,UGTs)是人体Ⅱ相反应中最重要的酶之一,利用葡萄糖醛酸为糖基供体催化广泛的内源性和外源性化学物质进行结合反应,增加其极性而利于排出体外。3) UGT1A9 尿苷二磷酸葡醛酸转移酶1A94) URIDINE DIPHOSPHATE GLUCURONOSYL TRANSFERASE 1 A1/metab 尿苷二磷...
尿苷二磷酸葡萄糖醛酸转移酶(UDP-glucuronosyltransferases,UGTs)是人体Ⅱ相反应中最重要的酶之一,利用葡萄糖醛酸为糖基供体催化广泛的内源性和外源性化学物质进行结合反应,增加其极性而利于排出体外。4) URIDINE DIPHOSPHATE GLUCURONOSYL TRANSFERASE 1 A1/metab 尿苷二磷酸葡萄糖醛酸转移酶/代谢5...