immunohistochemistryprognosisupper urinary tract urothelial carcinomauridine 5'diphospho‐glucuronosyltransferasedoi:10.1111/iju.13528John Wiley & Sons, LtdInternational Journal of Urology
The uridine diphosphoglucuronosyltransferases (UGTs) belong to a superfamily of enzymes that catalyse the glucuronidation of numerous endobiotics and xenobiotics. Several human hepatic and extrahepatic UGT isozymes have been characterized with respect to
OBJECTIVE: To determine the expression status of uridine 5'diphospho-glucuronosyltransferase 1A, a major phase II drug metabolism enzyme, in upper urinary tract urothelial carcinoma, as well as to assess its prognostic significance. METHODS: We immunohistochemically stained for uridine 5'diphospho-glu...
1.1 Name Glucuronosyltransferase,uridine diphosphoglucuronate-estradiol 1.2 CAS No. 37277-66-02. Realated Product InfomationUridine diphosphoglucuronic pyrophosphorylasecas:52228-05-4 Glucuronosyltransferase,uridine diphospho-cas:9030-08-4 Glucuronosyltransferase,bilirubin glucuronosidecas:71822-22-5 ...
Polymorphisms of the uri- dine-diphosphoglucuronosyltransferase 1A1 gene and coronary artery disease. Cell Mol Biol Lett 2008; 13: 1-10.Hsieh CJ, Chen MJ, Liao YL, Liao TN. Polymorphisms of the uridine- diphosphoglucuronosyltransferase 1A1 gene and coronary artery disease. Cell Mol Biol ...
Glucuronidation of curcuminoids by human microsomal and recombinant UDP-glucuronosyltransferases Glucuronidation is an important pathway in the metabolism of curcumin, but the isoforms of uridine-5鈥 -diphosphoglucuronosyltransferase (UGT) involved are ... SI Hoehle,E Pfeiffer,M Metzler - 《Molecular...
Uridine 5鈥diphospho-glucuronosyltransferases (UGTs) are expressed in the small intestines, but prediction of first-pass extraction from the related metabolism is not well studied. This work assesses physiologically based pharmacokinetic (PBPK) modeling as a tool for predicting intestinal metabolism due...
The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase I in Gilbert's syndrome. We sequenced the coding and promoter regions of the gene for bilirubin UDP-glucuronosyltransferase 1 (bilirubin/uridine diphosphoglucuronate-glucuronosyltransferase 1)--the only enzyme that ...
UDPGT UDP-glucuronosyltransferase 尿苷二磷酸葡萄糖醛酸转移酶 UDP-4-azido-4-deoxy-D-Glc 叠氮基-4-脱氧-D-葡萄糖 UDP- N- acetylglucosamine pyrophosphorylase UDP-N-乙酰葡萄糖胺焦磷酸化酶 UDP-GIcUA UDP-glucuronic acid UDP-葡萄糖醛酸 UDP-2FGal Uridine 5'-diphospho-(2-deoxy-2-fluoro)galactose...
UDP-glucuronosyltransferase activity toward bilirubin in the microsomal suspensions was assayed at 5 mM uridine diphosphoglucopyranuric acid by high pressure liquid chromatographic (HPLC) analysis of the products, as we have described previously(18). Formation of bilirubin glucuronides was proportional ...