Population geneticsDisease associationsMolecular evolutionNucleotide diversityEvolutionary modelsThis paper discusses the advantages provided by next generation sequencing (NGS) compared to traditional typings or limited sequencing strategies for the characterization of HLA population diversity based on four ...
90. Choy SH, Al-Mekhlafi HM, Mahdy MA, Nasr NN, Sulaiman M, Lim YAL, Surin J: Prevalence and associated risk factors of Giardia infection among indigenous communities in rural Malaysia. Sci Rep 2014, 4:6909. 91. Adam RD, Dahlstrom EW, Martens CA, Bruno DP, Barbia KD, Ricklefs SM...
2021). One of the KYNA analogs that has shown promising results is SZR-104, which can cross the blood-brain barrier and modulate the activity of KYNA receptors. SZR-104 is derived from KYNA and has similar neuroprotective and anti-inflammatory properties (Molnár et al. 2021; Szabo et al....
Analysis of intrinsic disorder propensity of membrane glycoprotein (M).aA 2.20 Å resolution crystal structure (PDB ID: 3I6G) of human SARS M protein (residues 88–96) in complex with A-2 α chain of HLA class I histocompatibility antigen and β2-microglobulin. Chains in this dimer correspo...
doi:10.1007/s12325-021-01685-yMathieu RoséIntissar BourahlaAlessandro GhiddiAssem Al-AkabawiMassoud ToussiAdvances in Therapy
Moreover, HLA region is the most polymorphic region in the human genome [87]. In certain medical procedures, such as hematopoietic cell transplants and solid organ transplants, NGS, particularly RNA-seq, may become a critical method of HLA typing [88]. Study on the Belarusian population ...