1服务器下载:23wget https://broad-ukb-sumstats-us-east-1.s3.amazonaws.com/round2/additive-tsvs/100001_irnt.gwas.imputed_v3.both_sexes.tsv.bgz -O 100001_irnt.gwas.imputed_v3.both_sexes.tsv.bgz45wget https://broad-ukb-sumstats-us-east-1.s3.amazonaws.com/round2/additive-tsvs/100001...
3wget https://broad-ukb-sumstats-us-east-1.s3.amazonaws.com/round2/additive-tsvs/100001_irnt.gwas.imputed_v3.both_sexes.tsv.bgz -O 100001_irnt.gwas.imputed_v3.both_sexes.tsv.bgz 4 5wget https://broad-ukb-sumstats-us-east-1.s3.amazonaws.com/round2/additive-tsvs/100001_raw.gwas...
3wget https://broad-ukb-sumstats-us-east-1.s3.amazonaws.com/round2/additive-tsvs/100001_irnt.gwas.imputed_v3.both_sexes.tsv.bgz -O 100001_irnt.gwas.imputed_v3.both_sexes.tsv.bgz 4 5wget https://broad-ukb-sumstats-us-east-1.s3.amazonaws.com/round2/additive-tsvs/100001_raw.gwas...
UKBBphenotype数据处理流程:https://github.com/Nealelab/UK_Biobank_GWAS/tree/master/imputed-v2-gwas phenotype 处理工具:Millard LAC, Davies NM, Gaunt TR, Davey Smith G, Tilling K. PHESANT: a tool for performing automated phenome scans in UK Biobank. bioRxiv (2017) https://github.com/astheegg...
8g<-fread("100001_irnt.gwas.imputed_v3.both_sexes.tsv.gz") 9 10# 查看 11head(f) 12head(g) 我们观察发现,两者共同点都没有rsID,两者最大的区别就是Beta值的不同,raw的Beta比较大,显然不符合我们做孟德尔随机化研究。 https://u.wechat.com/EJDqcVvs7ZjZauHDkTD8CSw (二维码自动识别)...