H. UDP-Glucuronosyltransferases. Pharmacol. Ther. 43:261–289; 1989.Burchell B, Coughtrie WH (1989) UPD-glucuronosyltransferases. Pharmacol Ther 43: 261–289 View ArticleBurchell B, Coughtrie MW. UDP-glucuronosyltransferases. Pharmacol Ther. 1989;43(2):261–89....
udp-glucuronosyltransferases网络尿苷二磷酸葡醛酸转移酶 网络释义 1. 尿苷二磷酸葡醛酸转移酶 ...用下被去毒化。在人体中,细胞色素-P450氧化酶、尿苷二磷酸葡醛酸转移酶(UDP-glucuronosyltransferases)和谷胱苷肽 …baike.baidu.com|基于42个网页©...
The UDP-glucuronosyltransferase (UGT) family catalyzes the glucuronidation of the glycosyl group of a nucleotide sugar to an acceptor compound (aglycone) at a nucleophilic functional group of oxygen (eg, hydroxyl or carboxylic acid groups), nitrogen (eg, amines), sulfur (eg, thiols), and ...
胃肠道UDP glucuronosyltransferases (UGTs)在抵御环境中外来生物的毒性作用中起着至关重要的作用。UGT1A8、UGT1A10等ugt主要在胃肠道组织中表达。 通过诱导UGT1A8和UGT1A10的表达,检测了雷洛昔芬在分化的Caco-2单分子膜中的II期代谢。本研究以黄芩中黄芩素、丹参素、黄芩素、黄芩素4种黄酮类化合物为模型化合物...
(1991). Role of UDP-glucuronosyltransferases in chemical carcinogenesis. Crit. Rev. Biochem. Mol. Biol. 26, 129-150.Bock, K. W. (1991) Roles of UDP-glucuronosyl transferases in chemical carcinogensis. Critical Reviews in Biochemistry and Molecular Biology , 26 129–50....
glucuronidation of androsterone (5alpha-androstane-3alpha-ol-17-one), etiocholanolone (5beta-androstane-3alpha-ol-17-one), 5alpha-androstane-3alpha-,17beta-diol (5alpha-diol), and 5beta-androstane-3alpha-, 17beta-diol (5beta-diol) by 19 recombinant human UDP-glucuronosyltransferases (...
The UDP-glucuronosyltransferase (UGT) family catalyzes the glucuronidation of the g... B Burchell,MWH Coughtrie - 《Pharmacology Therapeutics》 被引量: 729发表: 1989年 Human udp-glucuronosyltransferases: isoform selectivity and kinetics of 4-methylumbelliferone and 1-naphthol glucuronidation, effects...
Expression of UDP-glucuronosyltransferases (UGTs) 2B7 and 1A6 in the human brain and identification of 5-hydroxytryptamine as a substrate.Expression of UDP-glucuronosyltransferases (UGTs) 2B7 and 1A6 in the human brain and identification of 5-hydroxytryptamine as a substrate.UDP-glucuronosyltr...
英文名称:UDP-Glucuronosyltransferases,UGTs 英文同义词:UDP-Glucuronosyltransferases,UGTs CAS号: 分子式: 分子量:0 EINECS号: 信息错误报告 您的Email: 按国家浏览UDP-Glucuronosyltransferases,UGTs国外供应商中国供应商 UDP-Glucuronosyltransferases,UGTs推荐供应商 ...
β-lapachone (β-lap), an quinone oxidoreductase 1 (NQO1) targeting antitumor drug candidate in phase II clinical trials, is metabolically eliminated via NQO1 mediated quinone reduction and subsequent UDP-glucuronosyltransferases (UGTs) catalyzed glucuronidation. This study intends to explore the inner...