udp-glucuronosyltransferases网络尿苷二磷酸葡醛酸转移酶 网络释义 1. 尿苷二磷酸葡醛酸转移酶 ...用下被去毒化。在人体中,细胞色素-P450氧化酶、尿苷二磷酸葡醛酸转移酶(UDP-glucuronosyltransferases)和谷胱苷肽 …baike.baidu.com|基于42个网页©...
Renal UDP-glucuronosyltransferases and the glucuronidation of xenobiotics and endogenous media- tors. Drug Metab Rev. 2010;42(1):63-73.Kathleen M. Knights,John O. Miners.Renal UDP-glucuronosyltransferases and the glucuronidation of xenobiotics and endogenous mediators[J]. Drug Metabolism Reviews...
胃肠道UDP glucuronosyltransferases (UGTs)在抵御环境中外来生物的毒性作用中起着至关重要的作用。UGT1A8、UGT1A10等ugt主要在胃肠道组织中表达。 通过诱导UGT1A8和UGT1A10的表达,检测了雷洛昔芬在分化的Caco-2单分子膜中的II期代谢。本研究以黄芩中黄芩素、丹参素、黄芩素、黄芩素4种黄酮类化合物为模型化合物...
UDPGT|UDP-glucuronosyltransferase 尿苷二磷酸葡萄糖醛酸转移酶 西安齐岳生物科技公司*一大批糖化学产品包括单糖:阿洛糖、阿卓糖、阿拉伯糖、赤藓糖、果糖、岩藻糖、半乳糖、葡萄糖、古洛糖、艾杜糖、来苏糖、甘露糖、鼠李糖、核糖、塔罗糖、苏阿糖、木糖及其羧基化、氨基化、脱水脱氧化、卤素化等的衍生物。提供提...
Summary UDP-glucuronosyltransferases (UGTs) catalyse a major phase-II reaction of drug metabolism converting lipophilic xenobiotics (bilirubin, steroid hormones, retinoids etc.), drugs and dietary plant constituents into hydrophilic and excretable conjugates. UGTs are bound to the endoplasmic reticulum ...
UDP-glucuronosyltransferases (UGTs) represent a family of enzymes that glucuronidate many internal substances and drugs. This family acts as a drug metabolism phase II reactor in the liver and comprises one of the major protective mechanisms from toxic chemical substances. UGTs have two subfamilie...
大约30余种UDP-葡糖醛酸转移酶已经被纯化,或克隆与表达,其中一些可以催化伯胺和叔胺的N-葡醛酸结合反应。 Of the more than 30 UDP-glucuronosyltransferases (UGTs) that have been purified or cloned and e...
3 reagents referenced in UDP-glucuronosyltransferase 1A determinates intracellular accumulation and anti-cancer effect of β-lapachone in human colon cancer cells.
网络释义 1. 葡萄糖醛酸基转移酶 三亚蟎对葡萄糖醛酸基转移酶(UDP-Glucuronosyltransferase)在雄及雌性大鼠均呈剂量关系,同时雄性大鼠分别增加39%及0.8 … ntur.lib.ntu.edu.tw|基于3个网页 2. 葡萄糖醛酸转移酶 ...许的胆红素葡糖醛酸(bilirubin glucuronides)。肝脏组织的分析中并无残余葡萄糖醛酸转移酶...
The UDP-glucuronosyltransferases (UGT) are enzymes that conjugate glucuronic acid to nucleophilic O, N, S, and C atoms on lipophilic compounds via a nucleophilic bimolecular (S N 2) mechanism. The aglycone substrates glucuronidated include drugs, environmental toxins, and endogenous compounds such...